|
rs1799964
|
LTA;TNF;LOC100287329
|
Crohn Disease
|
C |
0.800 |
GeneticVariation |
GWASDB |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Crohn Disease
|
C |
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
|
rs1800630
|
LTA;TNF;LOC100287329
|
Rheumatoid Arthritis
|
|
0.720 |
GeneticVariation |
BEFREE |
The lack of positive association of TNF-α -863(rs1800630) polymorphism in our study group implies that TNF-α -863 polymorphism is not a susceptible marker to RA and cannot serve as a genetic factor for screening RA patients in Pakistan.
|
30899307 |
2019 |
|
rs1800630
|
LTA;TNF;LOC100287329
|
Rheumatoid Arthritis
|
|
0.720 |
GeneticVariation |
BEFREE |
Recent advances have highlighted a major genetic contribution to the pathogenesis of rheumatoid arthritis (RA).The aim of this study was to investigate whether polymorphisms of TNF-α (rs1800630, rs1800629) and TNFR1 (rs767455) were associated with susceptibility to and clinical outcome of RA in Chinese Han population.
|
25263964 |
2014 |
|
rs1800630
|
LTA;TNF;LOC100287329
|
Rheumatoid Arthritis
|
|
0.720 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs1041981
|
LTA;LOC100287329
|
Myocardial Infarction
|
|
0.720 |
GeneticVariation |
BEFREE |
Minor homozygous genotypes of polymorphisms in BAT1 (rs2239527, -23C/G), NFKBIL1 (rs2071592, -63T/A) and LTA (rs1800683, -162G/A; rs909253, 252G/A; rs1041981, Thr26Asn) were associated with moderately protective effects against myocardial infarction (P </= 0.045).
|
17517687 |
2007 |
|
rs1041981
|
LTA;LOC100287329
|
Myocardial Infarction
|
|
0.720 |
GeneticVariation |
BEFREE |
A recent large-scale, genome-wide association study of single nucleotide polymorphisms showed a strong association between susceptibility to myocardial infarction and the Thr26Asn polymorphism in the lymphotoxin-alpha (LTA) gene.
|
15973460 |
2005 |
|
rs1041981
|
LTA;LOC100287329
|
Myocardial Infarction
|
A |
0.720 |
SusceptibilityMutation |
CLINVAR |
|
|
|
|
rs2239704
|
LTA;LOC100287329
|
Cervix carcinoma
|
A |
0.710 |
GeneticVariation |
GWASCAT |
Defining the genetic susceptibility to cervical neoplasia-A genome-wide association study.
|
28806749 |
2017 |
|
rs2239704
|
LTA;LOC100287329
|
Cervix carcinoma
|
|
0.710 |
GeneticVariation |
BEFREE |
The rare allele (A) of SNP rs2239704 in the 5' UTR of the LTA gene was significantly associated with increased risks of cervical cancer (OR=1.31, 95% CI: 1.15-1.50; adjusted p-value: 0.013) and vulvar cancer (OR=1.51, 95% CI: 1.30-1.75; adjusted p-value: 1.9 × 10(-5) ).
|
23824834 |
2014 |
|
rs2516392
|
LTA;LOC100287329
|
Oral Ulcer
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci.
|
30837455 |
2019 |
|
rs2844482
|
LTA;LOC100287329
|
Asthma
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
rs3093539
|
LTA;LOC100287329
|
Asthma
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
rs190775951
|
LTA;LOC100287329
|
Blood Protein Measurement
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs2071590
|
LTA;LOC100287329
|
mathematical ability
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
|
30038396 |
2018 |
|
rs28732143
|
LTA;LOC100287329
|
Blood Protein Measurement
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs2229094
|
LTA;LOC100287329
|
White Blood Cell Count procedure
|
C |
0.700 |
GeneticVariation |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
rs2229094
|
LTA;LOC100287329
|
Lymphocyte Count measurement
|
C |
0.700 |
GeneticVariation |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
rs1041981
|
LTA;LOC100287329
|
Lupus Erythematosus, Systemic
|
A |
0.700 |
GeneticVariation |
GWASDB |
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
|
24871463 |
2014 |
|
rs2009658
|
LTA;LOC100287329
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs2844482
|
LTA;LOC100287329
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs2844484
|
LTA;LOC100287329
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
|
19503088 |
2009 |
|
rs1041981
|
LTA;LOC100287329
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
|
rs2516390
|
LTA;LOC100287329
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
|
rs2844484
|
LTA;LOC100287329
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |