MAPT, microtubule associated protein tau, 4137

N. diseases: 469; N. variants: 292
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs8070723
rs8070723
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.800 GeneticVariation GWASDB Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes. 24842889 2014
dbSNP: rs8070723
rs8070723
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.800 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs8070723
rs8070723
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.800 GeneticVariation GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs8070723
rs8070723
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.800 GeneticVariation GWASDB Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. 21044948 2011
dbSNP: rs8070723
rs8070723
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.800 GeneticVariation GWASCAT Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. 21044948 2011
dbSNP: rs8070723
rs8070723
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.800 GeneticVariation GWASDB Genome-wide association study reveals genetic risk underlying Parkinson's disease. 19915575 2009
dbSNP: rs62063857
rs62063857
Entrez Id: 4137;246744
Gene Symbol: MAPT;STH
MAPT;STH
CUI: C0030567
Disease:
Parkinson Disease
0.730 GeneticVariation BEFREE The four previously reported Parkinson's disease (PD)-related single-nucleotide polymorphisms (SNPs) - rs1775143, rs823114, rs2071746 and rs62063857 - have rarely been studied in Chinese Han populations. 28535700 2017
dbSNP: rs62063857
rs62063857
Entrez Id: 4137;246744
Gene Symbol: MAPT;STH
MAPT;STH
CUI: C0030567
Disease:
Parkinson Disease
0.730 GeneticVariation BEFREE Consequently, the rs62063857 polymorphism of the saitohin gene is a genetic risk factor for Parkinson's disease. 25168738 2015
dbSNP: rs1052553
rs1052553
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.730 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs62063857
rs62063857
Entrez Id: 4137;246744
Gene Symbol: MAPT;STH
MAPT;STH
CUI: C0030567
Disease:
Parkinson Disease
0.730 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs1052553
rs1052553
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.730 GeneticVariation BEFREE All 4 SNCA SNPs and the MAPT H1-haplotype-defining SNP (rs1052553) displayed a highly significant marginal association with PD at the significance level adjusted for multiple comparisons. 21391235 2011
dbSNP: rs1052553
rs1052553
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.730 GeneticVariation BEFREE Our findings indicate that as previously reported, the SNCA rs356219-G allele and MAPT rs1052553 (H1 haplotype) were both associated with an increased risk of PD, whilst contrary to previous reports, GSK3B variants were not. 21159074 2011
dbSNP: rs1052553
rs1052553
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.730 GeneticVariation BEFREE We identified a significant association between H1/H2 and risk of PD (rs1052553 OR: 1.43, CI: 1.23-1.64; rs62063857 OR: 1.45, CI: 1.27-1.67), but no effect of the H1-specific SNP rs242557 (OR: 0.92, CI: 0.82-1.03). 19912324 2010
dbSNP: rs62063857
rs62063857
Entrez Id: 4137;246744
Gene Symbol: MAPT;STH
MAPT;STH
CUI: C0030567
Disease:
Parkinson Disease
0.730 GeneticVariation BEFREE We identified a significant association between H1/H2 and risk of PD (rs1052553 OR: 1.43, CI: 1.23-1.64; rs62063857 OR: 1.45, CI: 1.27-1.67), but no effect of the H1-specific SNP rs242557 (OR: 0.92, CI: 0.82-1.03). 19912324 2010
dbSNP: rs17649553
rs17649553
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.720 GeneticVariation BEFREE Five out of the 13 tested SNPs (rs12185268, rs6599389, rs356220, rs13312, and rs17649553) were confirmed to be nominally significantly associated (<i>P</i> < 0.05) with PD risk in the Cypriot population. 31681140 2019
dbSNP: rs17649553
rs17649553
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
C 0.720 GeneticVariation GWASCAT A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci. 28892059 2017
dbSNP: rs17649553
rs17649553
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.720 GeneticVariation BEFREE Here, in order to discover potential AD-related loci, we investigated the association between late-onset AD (LOAD) susceptibility and nine single-nucleotide polymorphisms (SNPs) (rs11724635 of BST1, rs12637471 of MCCC1, rs15553999 of TMEM229, rs17649553 of MAPT, rs34311866 of TMEM175-GAK-DGKQ, rs356182 of SNCA, rs6430538 of ACMSD-TMEM163, rs76904798 of LRRK2 and rs823118 of RAB7L1-NUCKS1) which were reported to have genome-wide significant associations with PD risk in a recent Genome Wide Association Study performed among white population. 26738859 2017
dbSNP: rs17649553
rs17649553
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
C 0.720 GeneticVariation GWASCAT Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. 25064009 2014
dbSNP: rs1800547
rs1800547
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.720 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs1800547
rs1800547
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.720 GeneticVariation BEFREE Single-nucleotide polymorphisms in MAPT (rs1800547; P = 3.1 × 10(-4) ) and SNCA (rs356219; P = 5.5 × 10(-4) ) were significantly associated with Parkinson's disease. 21425343 2011
dbSNP: rs1800547
rs1800547
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.720 GeneticVariation GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs1800547
rs1800547
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.720 GeneticVariation BEFREE After adjusting for multiple comparisons, SNP rs1800547 was significantly associated with PD affection. 18509094 2008
dbSNP: rs17563986
rs17563986
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.700 GeneticVariation GWASDB Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes. 24842889 2014
dbSNP: rs10445337
rs10445337
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.700 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs10445338
rs10445338
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0030567
Disease:
Parkinson Disease
0.700 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012