|
rs17878931
|
MMP1;WTAPP1
|
Blood Protein Measurement
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
|
rs2075847
|
MMP1;WTAPP1
|
Triglycerides measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs2075847
|
MMP1;WTAPP1
|
Serum HDL cholesterol measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs2075847
|
MMP1;WTAPP1
|
High density lipoprotein measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs781662103
|
MMP1;WTAPP1
|
Glaucoma, Primary Open Angle
|
|
0.030 |
GeneticVariation |
BEFREE |
The aim of presented work was to analyze the impact of particular polymorphic changes in the promoter regions of the -1607 1G/2G MMP1, -1562 C/T MMP9, -82 A/G MMP12, -511 C/T IL-1β, and 372 T/C TIMP1 genes on their expression level in POAG patients.
|
26120586 |
2015 |
|
rs781662103
|
MMP1;WTAPP1
|
Glaucoma, Primary Open Angle
|
|
0.030 |
GeneticVariation |
BEFREE |
Normal RA value was observed in patients with POAG group connected with the 372 T/C TIMP1 (anova, p < 0.05) and the -511 C/T IL-1β (anova, p < 0.05) genes polymorphisms occurrence.
|
23800300 |
2013 |
|
rs781662103
|
MMP1;WTAPP1
|
Glaucoma, Primary Open Angle
|
|
0.030 |
GeneticVariation |
BEFREE |
Association of MMP1-1607 1G/2G and TIMP1 372 T/C gene polymorphisms with risk of primary open angle glaucoma in a Polish population.
|
21709637 |
2011 |
|
rs1799750
|
MMP1;WTAPP1
|
Coronary Artery Disease
|
|
0.020 |
GeneticVariation |
BEFREE |
This examination, as the first study of its own kind in Iranian Turks, reported association between MMP-1 (rs1799750) -1607 2G/2G and MMP-3 (rs3025058) -1612 6A/6A genotypes and CAD risk in patients older than 50 years.
|
31356534 |
2019 |
|
rs1799750
|
MMP1;WTAPP1
|
Degenerative polyarthritis
|
|
0.020 |
GeneticVariation |
BEFREE |
<b>Conclusion.</b> We systematically investigated the association between MMP-1-1607 (rs1799750) 1G/2G polymorphism and OA susceptibility; however, the results show no correlation.
|
30886066 |
2019 |
|
rs1799750
|
MMP1;WTAPP1
|
Coronary heart disease
|
|
0.020 |
GeneticVariation |
BEFREE |
Association of MMP-1 (rs1799750)-1607 2G/2G and MMP-3 (rs3025058)-1612 6A/6A Genotypes With Coronary Artery Disease Risk Among Iranian Turks.
|
31356534 |
2019 |
|
rs1799750
|
MMP1;WTAPP1
|
Degenerative polyarthritis
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, this case-control study confirms that <i>MMP-1</i> gene rs1799750 polymorphism increases the risk of knee OA in Chinese Han population.
|
30177524 |
2018 |
|
rs1799750
|
MMP1;WTAPP1
|
Osteoarthritis, Knee
|
|
0.020 |
GeneticVariation |
BEFREE |
The association between MMP-1 gene rs1799750 polymorphism and knee osteoarthritis risk.
|
30177524 |
2018 |
|
rs1799750
|
MMP1;WTAPP1
|
Glaucoma, Primary Open Angle
|
|
0.020 |
GeneticVariation |
BEFREE |
Subgroup analyses showed that the rs1799750 was significantly associated with primary angle closure glaucoma under homozygote (OR = 2.23, 95% CI 1.03-4.83, p = 0.043) and allelic (OR = 1.61, 95% CI 1.07-2.42, P = 0.021) models, while it was significantly associated with primary open angle glaucoma (OR = 1.64, 95% CI 1.05-2.56, p = 0.030) and exfoliation glaucoma (OR = 1.42, 95% CI 1.02-1.97, p = 0.036) under recessive models.
|
27428613 |
2017 |
|
rs1799750
|
MMP1;WTAPP1
|
Coronary heart disease
|
|
0.020 |
GeneticVariation |
BEFREE |
Thus, MMP-1 rs1799750 may be involved in the development of coexisting T2DM and CHD in the Han Chinese population.
|
27323171 |
2016 |
|
rs1799750
|
MMP1;WTAPP1
|
Bladder Neoplasm
|
|
0.020 |
GeneticVariation |
BEFREE |
The majority of the research described in the present mini-review proves that the genetic polymorphism in the MMP1 (rs1799750) is the most widely studied, and suggests that the rare genotype, 2G2G, of that gene might show increased susceptibility for bladder cancer, especially among smokers.
|
24635493 |
2014 |
|
rs1799750
|
MMP1;WTAPP1
|
Coronary Artery Disease
|
|
0.020 |
GeneticVariation |
BEFREE |
Significantly more C-2G (rs498186-rs1799750) haplotypes (p=0.001 after Bonferroni corrections) were found in CAD subjects.
|
25372932 |
2014 |
|
rs1799750
|
MMP1;WTAPP1
|
Carcinoma of bladder
|
|
0.020 |
GeneticVariation |
BEFREE |
The majority of the research described in the present mini-review proves that the genetic polymorphism in the MMP1 (rs1799750) is the most widely studied, and suggests that the rare genotype, 2G2G, of that gene might show increased susceptibility for bladder cancer, especially among smokers.
|
24635493 |
2014 |
|
rs1799750
|
MMP1;WTAPP1
|
Osteoarthritis, Knee
|
|
0.020 |
GeneticVariation |
BEFREE |
The present study shows that MMP1 -1607 1G/2G (rs1799750) polymorphism might be a risk factor for knee osteoarthritis susceptibility in the Greek population.
|
24838892 |
2014 |
|
rs1799750
|
MMP1;WTAPP1
|
Malignant neoplasm of urinary bladder
|
|
0.020 |
GeneticVariation |
BEFREE |
The majority of the research described in the present mini-review proves that the genetic polymorphism in the MMP1 (rs1799750) is the most widely studied, and suggests that the rare genotype, 2G2G, of that gene might show increased susceptibility for bladder cancer, especially among smokers.
|
24635493 |
2014 |
|
rs1799750
|
MMP1;WTAPP1
|
Glaucoma, Primary Open Angle
|
|
0.020 |
GeneticVariation |
BEFREE |
Our data suggest that the MMP1 rs1799750 (-1607 1G/2G) and MMP9 rs17576 polymorphisms might be of value for further study as potential gender-dependent risk factors for developing POAG and PACG, respectively, in Pakistan.
|
23441116 |
2013 |
|
rs1799750
|
MMP1;WTAPP1
|
Malignant neoplasm of urinary bladder
|
|
0.020 |
GeneticVariation |
BEFREE |
To elucidate genetic polymorphisms of the matrix metalloproteinases (MMPs) MMP1 (rs1799750), MMP2 (rs243865), MMP9 (rs3918242), MMP12 (rs2276109) and tissue inhibitors of MMPs (TIMPs) TIMP1 (rs2070584) and TIMP3 (rs9619311) genes that may be involved in susceptibility to bladder cancer (BC).
|
23819551 |
2013 |
|
rs1799750
|
MMP1;WTAPP1
|
Bladder Neoplasm
|
|
0.020 |
GeneticVariation |
BEFREE |
To elucidate genetic polymorphisms of the matrix metalloproteinases (MMPs) MMP1 (rs1799750), MMP2 (rs243865), MMP9 (rs3918242), MMP12 (rs2276109) and tissue inhibitors of MMPs (TIMPs) TIMP1 (rs2070584) and TIMP3 (rs9619311) genes that may be involved in susceptibility to bladder cancer (BC).
|
23819551 |
2013 |
|
rs1799750
|
MMP1;WTAPP1
|
Carcinoma of bladder
|
|
0.020 |
GeneticVariation |
BEFREE |
To elucidate genetic polymorphisms of the matrix metalloproteinases (MMPs) MMP1 (rs1799750), MMP2 (rs243865), MMP9 (rs3918242), MMP12 (rs2276109) and tissue inhibitors of MMPs (TIMPs) TIMP1 (rs2070584) and TIMP3 (rs9619311) genes that may be involved in susceptibility to bladder cancer (BC).
|
23819551 |
2013 |
|
rs1008478272
|
MMP1;WTAPP1
|
Osteomyelitis
|
|
0.010 |
GeneticVariation |
BEFREE |
CTSG N125S (AG) genotype was significantly more frequent among osteomyelitis patients than controls (15.5% vs. 9.4%, p = 0.014).
|
31647805 |
2019 |
|
rs1799750
|
MMP1;WTAPP1
|
Rotator cuff syndrome
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, a significant correlation was identified between the MMP-1 rs1799750 polymorphism</span> and RCT.
|
31652448 |
2019 |