MMP3, matrix metallopeptidase 3, 4314

N. diseases: 473; N. variants: 24
Disease: Ulcerative Colitis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs522616
rs522616
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0009324
Disease:
Ulcerative Colitis 		0.010 GeneticVariation BEFREE However, progression to death or liver transplant was significantly associated with homozygosity for minor alleles of rs522616, rs650108 and rs683878, particularly among PSC patients with concurrent ulcerative colitis (UC) (strongest in redundant SNPs rs650108/rs683878, hazard ratio=3.23, 95% confidence interval 1.45-7.25, P=0.004). 21134112 2011
dbSNP: rs650108
rs650108
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0009324
Disease:
Ulcerative Colitis 		0.010 GeneticVariation BEFREE However, progression to death or liver transplant was significantly associated with homozygosity for minor alleles of rs522616, rs650108 and rs683878, particularly among PSC patients with concurrent ulcerative colitis (UC) (strongest in redundant SNPs rs650108/rs683878, hazard ratio=3.23, 95% confidence interval 1.45-7.25, P=0.004). 21134112 2011