MMP3, matrix metallopeptidase 3, 4314

N. diseases: 473; N. variants: 24
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3025058
rs3025058
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0162871
Disease:
Aortic Aneurysm, Abdominal
0.020 GeneticVariation BEFREE For SNPs that had previously been associated with AAA presence, meta-analysis of currently available data together with the two study cohorts disclosed positive associations for the MMP-3 rs3025058 (OR, 1.15; 95% CI, 1.06-1.25; P = .0009) and MTHFR rs1801133 (OR, 1.07; 95% CI, 1.02-1.12; P = .0088). 24613192 2015
dbSNP: rs3025058
rs3025058
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0162871
Disease:
Aortic Aneurysm, Abdominal
0.020 GeneticVariation BEFREE Results on 1258 cases and 1406 controls for MMP3 rs3025058 showed an association with AAA presence; best described by a dominant pattern of inheritance (OR=1.48 95%CI 1.23 - 1.78, p=3.95×10-5). 23813847 2014