CCND1, cyclin D1, 595

N. diseases: 859; N. variants: 12
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0026764
Disease:
Multiple Myeloma
0.710 GeneticVariation BEFREE In AL amyloidosis, rs9344 at the splice site of cyclin D1, promoting translocation (11;14), reached the highest significance, P=7.80 × 10<sup>-11</sup>; the SNP was only marginally significant in MM. 28025584 2017
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0026764
Disease:
Multiple Myeloma
0.710 GeneticVariation GWASDB The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma. 23502783 2013
dbSNP: rs3017621
rs3017621
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0205682
Disease:
Waist-Hip Ratio
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs3212880
rs3212880
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0005890
Disease:
Body Height
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs3918292
rs3918292
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0005890
Disease:
Body Height
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs34507830
rs34507830
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0678222
Disease:
Breast Carcinoma
T 0.700 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0268381
Disease:
Primary amyloidosis
G 0.700 GeneticVariation GWASCAT Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. 28679651 2017
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0268381
Disease:
Primary amyloidosis
G 0.700 GeneticVariation GWASCAT In AL amyloidosis, rs9344 at the splice site of cyclin D1, promoting translocation (11;14), reached the highest significance, P=7.80 × 10<sup>-11</sup>; the SNP was only marginally significant in MM. 28025584 2017
dbSNP: rs603965
rs603965
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0026764
Disease:
Multiple Myeloma
G 0.700 GeneticVariation GWASCAT The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma. 23502783 2013
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C1858438
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO
A 0.700 SusceptibilityMutation CLINVAR
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C3805838
Disease:
VON HIPPEL-LINDAU SYNDROME, MODIFIER OF
A 0.700 SusceptibilityMutation CLINVAR
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C3810481
Disease:
MULTIPLE MYELOMA, t(11;14) TYPE, SUSCEPTIBILITY TO
A 0.700 SusceptibilityMutation CLINVAR
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C4048328
Disease:
cervical cancer
0.040 GeneticVariation BEFREE However, in case of cervical cancer risk a non-significant association was reported under the recessive model (GG+GA vs AA: OR = 1.52, 95%CI = 0.60-3.90, <i>P</i>=0.38) with reference to <i>CCND1</i> polymorphism (rs9344). 30361291 2018
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0302592
Disease:
Cervix carcinoma
0.040 GeneticVariation BEFREE However, in case of cervical cancer risk a non-significant association was reported under the recessive model (GG+GA vs AA: OR = 1.52, 95%CI = 0.60-3.90, <i>P</i>=0.38) with reference to <i>CCND1</i> polymorphism (rs9344). 30361291 2018
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007847
Disease:
Malignant tumor of cervix
0.040 GeneticVariation BEFREE However, in case of cervical cancer risk a non-significant association was reported under the recessive model (GG+GA vs AA: OR = 1.52, 95%CI = 0.60-3.90, <i>P</i>=0.38) with reference to <i>CCND1</i> polymorphism (rs9344). 30361291 2018
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007847
Disease:
Malignant tumor of cervix
0.040 GeneticVariation BEFREE This study indicates that CCND1 rs9344 polymorphisms confer host susceptibility to cervical cancer. 21594903 2012
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C4048328
Disease:
cervical cancer
0.040 GeneticVariation BEFREE This study indicates that CCND1 rs9344 polymorphisms confer host susceptibility to cervical cancer. 21594903 2012
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0302592
Disease:
Cervix carcinoma
0.040 GeneticVariation BEFREE This study indicates that CCND1 rs9344 polymorphisms confer host susceptibility to cervical cancer. 21594903 2012
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0302592
Disease:
Cervix carcinoma
0.040 GeneticVariation BEFREE We examined the distribution of the CCND1 A870G (rs9344) polymorphic variant in patients with cervical cancer (n = 129) and healthy individuals (n = 288) in a sample of a Polish cohort. 20680537 2011
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C4048328
Disease:
cervical cancer
0.040 GeneticVariation BEFREE We examined the distribution of the CCND1 A870G (rs9344) polymorphic variant in patients with cervical cancer (n = 129) and healthy individuals (n = 288) in a sample of a Polish cohort. 20680537 2011
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007847
Disease:
Malignant tumor of cervix
0.040 GeneticVariation BEFREE We examined the distribution of the CCND1 A870G (rs9344) polymorphic variant in patients with cervical cancer (n = 129) and healthy individuals (n = 288) in a sample of a Polish cohort. 20680537 2011
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C4048328
Disease:
cervical cancer
0.040 GeneticVariation BEFREE A significant association of CxCa with various polymorphisms was observed: rs1800797 in the IL-6 gene (odds ratio [OR] = 0.88, 95% confidence intervals [CI]: 0.79-0.99); rs1041981 in the LTA gene (OR = 0.87, 95% CI: 0.78-0.98), and rs9344 in the CCND1 gene (OR = 1.14, 95% CI: 1.02-1.27), for those individuals carrying the rare allele. 19585495 2009
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007847
Disease:
Malignant tumor of cervix
0.040 GeneticVariation BEFREE A significant association of CxCa with various polymorphisms was observed: rs1800797 in the IL-6 gene (odds ratio [OR] = 0.88, 95% confidence intervals [CI]: 0.79-0.99); rs1041981 in the LTA gene (OR = 0.87, 95% CI: 0.78-0.98), and rs9344 in the CCND1 gene (OR = 1.14, 95% CI: 1.02-1.27), for those individuals carrying the rare allele. 19585495 2009
dbSNP: rs9344
rs9344
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0302592
Disease:
Cervix carcinoma
0.040 GeneticVariation BEFREE A significant association of CxCa with various polymorphisms was observed: rs1800797 in the IL-6 gene (odds ratio [OR] = 0.88, 95% confidence intervals [CI]: 0.79-0.99); rs1041981 in the LTA gene (OR = 0.87, 95% CI: 0.78-0.98), and rs9344 in the CCND1 gene (OR = 1.14, 95% CI: 1.02-1.27), for those individuals carrying the rare allele. 19585495 2009
dbSNP: rs603965
rs603965
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0017638
Disease:
Glioma
0.020 GeneticVariation BEFREE Our findings suggested that CCND1 rs603965 polymorphism may serve as a potential genetic biomarker of brain tumor, especially for glioma. 30972946 2019