BCL2, BCL2 apoptosis regulator, 596

N. diseases: 1456; N. variants: 27
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		T 0.800 GeneticVariation GWASCAT Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. 30718926 2019
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.800 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590 2017
dbSNP: rs4987856
rs4987856
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		C 0.800 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. 26956414 2016
dbSNP: rs4987852
rs4987852
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		0.800 GeneticVariation GWASDB Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs4987852
rs4987852
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		0.800 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs4987855
rs4987855
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		G 0.800 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs4987855
rs4987855
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		G 0.800 GeneticVariation GWASDB Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs4987856
rs4987856
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		C 0.800 GeneticVariation GWASDB Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.800 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. 22325160 2012
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0205682
Disease:
Waist-Hip Ratio 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0871470
Disease:
Systolic Pressure 		T 0.700 GeneticVariation GWASCAT Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. 30578418 2019
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0871470
Disease:
Systolic Pressure 		T 0.700 GeneticVariation GWASCAT Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. 30224653 2018
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0202236
Disease:
Triglycerides measurement 		T 0.700 GeneticVariation GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127 2018
dbSNP: rs533722308
rs533722308
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0600139
Disease:
Prostate carcinoma 		CT 0.700 GeneticVariation GWASCAT Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 29892016 2018
dbSNP: rs7226979
rs7226979
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0019572
Disease:
Hirsutism 		C 0.700 GeneticVariation GWASCAT Excessive hairiness signals' top SNPs were also eQTLs for TBX15 (rs984225; P = 1.6 × 10<sup>-8</sup>), BCL2 (rs7226979; P = 7.3 × 10<sup>-11</sup>), and GCC2 and LIMS1 (rs6542772; P = 2.2 × 10<sup>-9</sup>). 29895819 2018
dbSNP: rs8094630
rs8094630
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C2985280
Disease:
Blood Protein Measurement 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C1305855
Disease:
Body mass index 		C 0.700 GeneticVariation GWASCAT Genome-wide association study identifies 112 new loci for body mass index in the Japanese population. 28892062 2017
dbSNP: rs4940576
rs4940576
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies novel susceptible loci and highlights Wnt/beta-catenin pathway in the development of adolescent idiopathic scoliosis. 28334814 2017