rs2107538
|
CCL5;LOC105371744
|
Blood Protein Measurement
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
rs2107538
|
CCL5;LOC105371744
|
Tuberculosis
|
|
0.020 |
GeneticVariation |
BEFREE |
Many case-control studies have been performed in the recent past to investigate the association between CCL5 -403 G>A (rs2107538) gene polymorphism and tuberculosis (TB) susceptibility in various ethnic groups.
|
24015211 |
2013 |
rs2280788
|
CCL5;LOC105371744
|
Tuberculosis
|
|
0.020 |
GeneticVariation |
BEFREE |
A genetic association study of CCL5 -28 C>G (rs2280788) polymorphism with risk of tuberculosis: a meta-analysis.
|
24376699 |
2013 |
rs2107538
|
CCL5;LOC105371744
|
Tuberculosis
|
|
0.020 |
GeneticVariation |
BEFREE |
The present study investigated the relationship between the RANTES polymorphisms (-28C/G; rs2280788, and -403G/A; rs2107538) and susceptibility to active tuberculosis (TB) in Tunisian populations.
|
21510799 |
2011 |
rs2280788
|
CCL5;LOC105371744
|
Tuberculosis
|
|
0.020 |
GeneticVariation |
BEFREE |
The present study investigated the relationship between the RANTES polymorphisms (-28C/G; rs2280788, and -403G/A; rs2107538) and susceptibility to active tuberculosis (TB) in Tunisian populations.
|
21510799 |
2011 |
rs2107538
|
CCL5;LOC105371744
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation |
BEFREE |
Novel associations of the polymorphic loci in CCL20 (rs6749704) and CCL5 (rs2107538) genes with type 2 diabetes had been identified as a result of the conducted research.
|
30536157 |
2019 |
rs2107538
|
CCL5;LOC105371744
|
Benign Prostatic Hyperplasia
|
|
0.010 |
GeneticVariation |
BEFREE |
The CCL5 rs2107538 polymorphism was identified to be associated with a significantly lower risk of BPH [A/G vs. G/G: odds ratio (OR)=0.37, 95% confidence interval (CI)=0.17‑0.78; A/A + A/G vs. G/G: OR=0.39, 95% CI=0.19‑0.79; A vs. G: OR=0.58, 95% CI=0.35‑0.96).
|
30816510 |
2019 |
rs3817655
|
CCL5;LOC105371744
|
Hepatitis C
|
|
0.010 |
GeneticVariation |
BEFREE |
Susceptibility to HCV infection is associated with A alleles of both (rs743660 and rs1799864 G/A) of CCR2 while spontaneous clearance of HCV is associated with the C allele of rs13900 of CCL2 and T allele of rs3817655 of CCL5.
|
30175654 |
2019 |
rs2280789
|
CCL5;LOC105371744
|
Tuberculosis, Pulmonary
|
|
0.010 |
GeneticVariation |
BEFREE |
Regulatory role of CCL5 (rs2280789) and CXCL10 (rs56061981) gene polymorphisms on intracellular CCL5 and CXCL10 expression in pulmonary tuberculosis.
|
28336310 |
2018 |
rs2280789
|
CCL5;LOC105371744
|
Tuberculosis
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study suggest that TT genotype of CCL5 In1.1T/C (rs2280789) polymorphism play an important role to increased CCL5 expression in T cell which may enhanced Th1 immunity and help in protection against tuberculosis.
|
28336310 |
2018 |
rs3817656
|
CCL5;LOC105371744
|
Hepatitis C
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphism of CCR1 rs3733096 and CCL5 rs3817656 are associated with spontaneous clearance of HCV in Chinese Han population.
|
29703961 |
2018 |
rs2107538
|
CCL5;LOC105371744
|
Respiration Disorders
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms of -403G/A (rs2107538), -28C/G (rs2280788), and In1.1T/C (rs2280789) in chemotactic chemokine ligand 5 (CCL5) have linked with many respiratory diseases.
|
26304916 |
2015 |
rs2280789
|
CCL5;LOC105371744
|
Respiration Disorders
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms of -403G/A (rs2107538), -28C/G (rs2280788), and In1.1T/C (rs2280789) in chemotactic chemokine ligand 5 (CCL5) have linked with many respiratory diseases.
|
26304916 |
2015 |
rs2107538
|
CCL5;LOC105371744
|
Breast Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
The purpose of this study was to investigate whether single nucleotide polymorphisms of CCL5 -403 G>A (rs2107538) and CCR5 Δ32 genes are associated with the breast cancer (BC) risk.
|
25171476 |
2014 |
rs2107538
|
CCL5;LOC105371744
|
Malignant neoplasm of breast
|
|
0.010 |
GeneticVariation |
BEFREE |
The purpose of this study was to investigate whether single nucleotide polymorphisms of CCL5 -403 G>A (rs2107538) and CCR5 Δ32 genes are associated with the breast cancer (BC) risk.
|
25171476 |
2014 |
rs2107538
|
CCL5;LOC105371744
|
Papillary thyroid carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
When the genetic relationships between SNP and subgroups of PTC patients were assessed, SNP rs2107538 in CCL5 was not associated with any clinicopathologic characteristics of PTC.
|
23957698 |
2013 |
rs2107538
|
CCL5;LOC105371744
|
Ischemic stroke
|
|
0.010 |
GeneticVariation |
BEFREE |
This is a pilot study analysing association of chemokine gene polymorphisms (CXCL1, rs3117604; CXCL2, rs3806792; CCL2, rs2857656 and rs3760396; CCL5, rs2107538) in Korean patients with ischemic stroke (IS) (n = 120) and age-matched controls (n = 267).
|
23198952 |
2013 |
rs2107538
|
CCL5;LOC105371744
|
Active tuberculosis
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study investigated the relationship between the RANTES polymorphisms (-28C/G; rs2280788, and -403G/A; rs2107538) and susceptibility to active tuberculosis (TB) in Tunisian populations.
|
21510799 |
2011 |
rs2280788
|
CCL5;LOC105371744
|
Active tuberculosis
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study investigated the relationship between the RANTES polymorphisms (-28C/G; rs2280788, and -403G/A; rs2107538) and susceptibility to active tuberculosis (TB) in Tunisian populations.
|
21510799 |
2011 |
rs2107538
|
CCL5;LOC105371744
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.010 |
GeneticVariation |
BEFREE |
We tested RANTES as a candidate gene for association with T1D using three single-nucleotide polymorphism (SNP) variants (rs4251719, rs2306630 and rs2107538) to capture haplotype information.
|
16855620 |
2006 |
rs766662990
|
CCL5;LOC105371744
|
HIV-1 infection
|
|
0.010 |
GeneticVariation |
BEFREE |
Four SNPs (CCR2-V64I, CCR5-2459, MIP1A+954, and IL2+3896) and specific haplotypes in the IL2 and CCR2/CCR5 regions were significantly associated with HIV-1 infection susceptibility in different genetic models.
|
16323127 |
2006 |
rs766662990
|
CCL5;LOC105371744
|
Anthracosis
|
|
0.010 |
GeneticVariation |
BEFREE |
Associations of polymorphisms in CCL5 (G-403A) and its receptor CCR5 (Delta32), CCL2 (A-2578G) and CCR2 (V64I), and CX3CR1 V249I and T280M with coal worker's pneumoconiosis (CWP) were investigated in 209 miners examined in 1990, 1994 and 1999.
|
16524739 |
2006 |
rs766662990
|
CCL5;LOC105371744
|
Alzheimer Disease, Late Onset
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined whether DNA-polymorphisms at the genes encoding chemokines MCP-1 (-2518 A/G) and RANTES (-403 A/G), and chemokine receptors 5 (CCR5, Delta32) and 2 (CCR2,V64I), were associated with the risk and/or the clinical outcome of LOAD and PD.
|
15488313 |
2004 |
rs766662990
|
CCL5;LOC105371744
|
Parkinson Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined whether DNA-polymorphisms at the genes encoding chemokines MCP-1 (-2518 A/G) and RANTES (-403 A/G), and chemokine receptors 5 (CCR5, Delta32) and 2 (CCR2,V64I), were associated with the risk and/or the clinical outcome of LOAD and PD.
|
15488313 |
2004 |