TCF7L2, transcription factor 7 like 2, 6934

N. diseases: 257; N. variants: 70
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7901695
rs7901695
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C1956346
Disease:
Coronary Artery Disease
T 0.700 GeneticVariation GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018
dbSNP: rs7903146
rs7903146
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C1956346
Disease:
Coronary Artery Disease
0.030 GeneticVariation BEFREE These results suggest that TCF7L2 variants rs7903146 rs12255372, and rs11196205 are significantly associated with angiographically diagnosed CAD, specifically in patients with T2DM. 21423583 2011
dbSNP: rs7903146
rs7903146
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C1956346
Disease:
Coronary Artery Disease
0.030 GeneticVariation BEFREE rs7903146 T allele is associated with diabetes and, in non-diabetic individuals, with a higher prevalence and severity of coronary artery disease and cardiovascular events. name of registry site (see list below), registration number, trial registration URL in brackets. 19924244 2009
dbSNP: rs7903146
rs7903146
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C1956346
Disease:
Coronary Artery Disease
0.030 GeneticVariation BEFREE TCF7L2 rs7903146 T allele is associated with a 1.57 increased risk for type 2 diabetes in a Brazilian cohort of patients with known coronary heart disease. 19055834 2008
dbSNP: rs11196205
rs11196205
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C1956346
Disease:
Coronary Artery Disease
0.010 GeneticVariation BEFREE These results suggest that TCF7L2 variants rs7903146 rs12255372, and rs11196205 are significantly associated with angiographically diagnosed CAD, specifically in patients with T2DM. 21423583 2011
dbSNP: rs12255372
rs12255372
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C1956346
Disease:
Coronary Artery Disease
0.010 GeneticVariation BEFREE These results suggest that TCF7L2 variants rs7903146 rs12255372, and rs11196205 are significantly associated with angiographically diagnosed CAD, specifically in patients with T2DM. 21423583 2011