VEGFA, vascular endothelial growth factor A, 7422

N. diseases: 1899; N. variants: 59
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs138551969
rs138551969
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0201976
Disease:
Creatinine measurement, serum (procedure)
0.700 GeneticVariation GWASCAT Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population. 29124443 2018
dbSNP: rs138551969
rs138551969
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0017654
Disease:
Glomerular Filtration Rate
0.700 GeneticVariation GWASCAT Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population. 29124443 2018
dbSNP: rs138551969
rs138551969
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0740394
Disease:
Hyperuricemia
0.700 GeneticVariation GWASCAT Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population. 29124443 2018
dbSNP: rs138551969
rs138551969
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0202239
Disease:
Uric acid measurement (procedure)
0.700 GeneticVariation GWASCAT Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population. 29124443 2018
dbSNP: rs3025021
rs3025021
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C2697758
Disease:
Interleukin 10 Measurement
C 0.700 GeneticVariation GWASCAT Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. 27989323 2017
dbSNP: rs833070
rs833070
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0014772
Disease:
Red Blood Cell Count measurement
C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs833070
rs833070
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0018935
Disease:
Hematocrit procedure
C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs833070
rs833070
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0518015
Disease:
Hemoglobin measurement
C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs2010963
rs2010963
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C2676832
Disease:
MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 1(finding)
G 0.700 SusceptibilityMutation CLINVAR
dbSNP: rs833061
rs833061
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0242383
Disease:
Age related macular degeneration
0.060 GeneticVariation BEFREE However, weak correlations between 10 SNPs (CFH rs1329428 TT genotype, CFH rs3753394 CC genotype and T allele, CFH rs1410996 AA genotype, CFH rs800292 AA genotype, CFH rs800292 A allele, VEGF rs833061 TT genotype and C allele, VEGF rs2010963 CG genotype, VEGFR2 rs1531289 TT genotype, ARMS2 rs10490924 TT genotype, KCTD10 rs238104 GC genotype, rs1531289 T allele and ARMS2 rs10490924 T allele) and AMD were shown. 30696427 2019
dbSNP: rs2010963
rs2010963
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C1956346
Disease:
Coronary Artery Disease
0.060 GeneticVariation BEFREE In summary, we concluded that the VEGF gene polymorphisms rs699947, rs2010963, and rs3025039 are correlated with an elevated CAD risk. 29973139 2018
dbSNP: rs2010963
rs2010963
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C1956346
Disease:
Coronary Artery Disease
0.060 GeneticVariation BEFREE Vascular endothelial growth factor rs20</span>10963 polymorphism may be associated with the presence of CAD and its long-term survival, but not with its severity. 27704620 2017
dbSNP: rs699947
rs699947
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011884
Disease:
Diabetic Retinopathy
0.060 GeneticVariation BEFREE The VEGF gene SNPs analyzed with regard to DR susceptibility were rs2010963 (G > C), rs833061 (T > C), rs699947 (C > A), rs3025039 (C > T) and rs1570360 (G > A). 27613596 2017
dbSNP: rs833061
rs833061
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0242383
Disease:
Age related macular degeneration
0.060 GeneticVariation BEFREE Significant associations with AMD risk were showed for rs833061, rs1413711, and rs3025039 polymorphisms but not for rs2010963. 27999450 2016
dbSNP: rs2010963
rs2010963
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C1956346
Disease:
Coronary Artery Disease
0.060 GeneticVariation BEFREE Our results indicated that ACE(rs4646994)-D allele alone and in the presence of VEGF(rs2010963)-G allele can be an important independent risk factor for susceptibility of CAD in T2DM patients even after correcting for conventional risk factors in a population of Iran. 24505095 2015
dbSNP: rs699947
rs699947
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011884
Disease:
Diabetic Retinopathy
0.060 GeneticVariation BEFREE After adjustment for covariates, significant association of DR remained with the homozygous genotype of the minor allele for the SNPs rs699947 (odds ratio [OR] = 3.54, 95% confidence interval [CI]: 1.12-11.19), rs833061 (OR = 3.72, 95% CI: 1.17-11.85), rs13207351 (OR = 3.76, 95% CI: 1.21-11.71), and rs2146323 (OR = 2.8, 95% CI: 1.46-5.37) in the VEGF gene as well as the SNP rs2071559 (OR = 1.62, 95% CI: 1.08-2.41) in the KDR gene. 24623964 2014
dbSNP: rs699947
rs699947
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011884
Disease:
Diabetic Retinopathy
0.060 GeneticVariation BEFREE No evidence of association was observed between -2578 A/C (rs699947), +405C/G (rs2010963), +936C/T (rs3025039), and DR risk under stringent Bonferroni's correction. 24534217 2014
dbSNP: rs833061
rs833061
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0242383
Disease:
Age related macular degeneration
0.060 GeneticVariation BEFREE The meta-analysis results based on nine case-control studies with 2427 cases and 2037 controls showed that rs833061 had protective effects on AMD risk (TT vs. CT+CC: OR=0.58, 95% CI=0.41-0.81), whereas rs1413711 (TT vs. CT+CC: OR=1.46, 95% CI=1.10-1.93) and rs3025039 (TT vs. CC: OR=1.87, 95% CI=1.15-3.02; TT vs. CT+CC: OR=2.09, 95% CI=1.30-3.37) represented as risk factors for AMD. 24689893 2014
dbSNP: rs2010963
rs2010963
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C1956346
Disease:
Coronary Artery Disease
0.060 GeneticVariation BEFREE The possible association of rs699947 and rs2010963 with CAD risks warrant confirmation in independent case-control studies and may be informative for future investigations on the pathogenesis of CAD. 23545315 2013
dbSNP: rs2010963
rs2010963
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C1956346
Disease:
Coronary Artery Disease
0.060 GeneticVariation BEFREE Logistic regression analyses revealed that the VEGFA rs699947 C/A, VEGFA rs2010963 G/C, and VEGFA rs3025039 C/T polymorphisms were not associated with a risk of CAD. 23880405 2013
dbSNP: rs699947
rs699947
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011884
Disease:
Diabetic Retinopathy
0.060 GeneticVariation BEFREE Our meta-analysis confirmed the significant association between rs699947 polymorphism and DR after exclusion of outliers, and rs2010963 polymorphism might be not associated with DR. 24131746 2013
dbSNP: rs833061
rs833061
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0242383
Disease:
Age related macular degeneration
0.060 GeneticVariation BEFREE Our study shows that VEGFA rs699947 and rs833061 and VEGFR2 rs2071559 polymorphisms do not modify the risk of suffering AMD in a Spanish population. 23971975 2013
dbSNP: rs833061
rs833061
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0242383
Disease:
Age related macular degeneration
0.060 GeneticVariation BEFREE The results suggest the VEGF-A rs1413711 and rs833061 polymorphisms may contribute to AMD susceptibility. 23761723 2013
dbSNP: rs699947
rs699947
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011884
Disease:
Diabetic Retinopathy
0.060 GeneticVariation BEFREE After adjusting for covariates, a significant association of DR was observed with the homozygous genotype of the minor allele for promoter SNPs rs699947 (odds ratio (OR)=3.54, 95% confidence interval (CI): 1.12-11.19), rs833061 (OR=3.72, 95% CI: 1.17-11.85) and rs13207351 (OR=3.76, 95% CI: 1.21-11.71). 22162628 2011
dbSNP: rs2010963
rs2010963
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C1956346
Disease:
Coronary Artery Disease
0.060 GeneticVariation BEFREE This study tested the association between functional VEGF +405 C>G (rs2010963), -2578C>A (rs699947) polymorphisms, and coronary collaterals in patients with coronary artery disease (CAD). 20621071 2010