CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Disease: Colorectal Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3834129
rs3834129
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.040 GeneticVariation BEFREE Overall, caspase-8 rs3834129 genotypes may not serve as predictors for CRC risk or prognosis. 31177115 2019
dbSNP: rs3834129
rs3834129
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.040 GeneticVariation BEFREE Taken together, we showed that <i>CASP8</i> rs3834129 polymorphism influences CRC susceptibility in a weak impact manner. 30519316 2018
dbSNP: rs3834129
rs3834129
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.040 GeneticVariation BEFREE Association between CASP8 -652 6N del polymorphism (rs3834129) and colorectal cancer risk: results from a multi-centric study. 24465592 2014
dbSNP: rs3834129
rs3834129
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.040 GeneticVariation BEFREE Polymorphisms in CASP8 at 2q33.1 have been associated with the risk of developing cancer, specifically, the D302H variant (rs1045485) with breast cancer in the European population and the -652 6N ins/del promoter variant (rs3834129) with multiple tumours including colorectal cancer (CRC) in the Chinese population. 18362937 2008
dbSNP: rs113686495
rs113686495
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.010 GeneticVariation BEFREE We aimed to discern potential association of these two variants and rs113686495 (CTGTCATT/-), as well as CASP8 mRNA and protein expression levels with colorectal cancer (CRC) in Han Chinese. 23844036 2013
dbSNP: rs1045485
rs1045485
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.010 GeneticVariation BEFREE It is thus very unlikely that variation in CASP8 defined by -652 6N ins/del or D302H influences the risk of CRC in European populations. 18362937 2008