CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10931936
rs10931936
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0025202
Disease:
melanoma
0.700 GeneticVariation GWASDB Genome-wide association study identifies three new melanoma susceptibility loci. 21983787 2011
dbSNP: rs3834129
rs3834129
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0025202
Disease:
melanoma
0.010 GeneticVariation BEFREE In a hospital-based study of 805 non-Hispanic white patients with CM and 835 cancer-free age-, sex-, and ethnicity-matched controls, we genotyped three reported putatively functional polymorphisms of CASP8 and CASP10-CASP8 D302 H (rs1045485:G>C), CASP8 -652 6N del (rs3834129:-/CTTACT), and CASP10 I522L (rs13006529:A>T)-and assessed their associations with risk of CM and interactions with known risk factors for CM. 18563783 2008