GDF15, growth differentiation factor 15, 9518

N. diseases: 389; N. variants: 3
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1058587
rs1058587
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
CUI: C0600139
Disease:
Prostate carcinoma
0.020 GeneticVariation BEFREE SNPs of CD44 (rs9666607), ABCC1 (rs35605 and rs212091) and GDF15 (rs1058587) were associated with PCa survival and predicted to be functional. 29726910 2018
dbSNP: rs1058587
rs1058587
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.020 GeneticVariation BEFREE SNPs of CD44 (rs9666607), ABCC1 (rs35605 and rs212091) and GDF15 (rs1058587) were associated with PCa survival and predicted to be functional. 29726910 2018
dbSNP: rs1058587
rs1058587
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
CUI: C0600139
Disease:
Prostate carcinoma
0.020 GeneticVariation BEFREE A recent study (JNCI 2004, 96:1248-1254) found marginal evidence of an association between the presence of the mature MIC-1 protein nonsynonymous polymorphism H6D C-to-G (rs1058587) with reduced prostate cancer risk [odds ratio, 0.83; 95% confidence interval (95% CI), 0.69-0.99]. 16775185 2006
dbSNP: rs1058587
rs1058587
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.020 GeneticVariation BEFREE A recent study (JNCI 2004, 96:1248-1254) found marginal evidence of an association between the presence of the mature MIC-1 protein nonsynonymous polymorphism H6D C-to-G (rs1058587) with reduced prostate cancer risk [odds ratio, 0.83; 95% confidence interval (95% CI), 0.69-0.99]. 16775185 2006
dbSNP: rs1804826
rs1804826
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
CUI: C0948008
Disease:
Ischemic stroke
0.010 GeneticVariation BEFREE The GDF-15 gene rs1804826G/T polymorphism and sGDF-15 levels are associated with IS in the Chinese population. 28526273 2017
dbSNP: rs1804826
rs1804826
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
CUI: C0948008
Disease:
Ischemic stroke
0.010 GeneticVariation BEFREE Compared with the rs1804826 G allele, the rs1804826 T allele was significantly associated with an increased risk of IS (P < .05). 28526273 2017
dbSNP: rs1058587
rs1058587
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
CUI: C0003873
Disease:
Rheumatoid Arthritis
0.010 GeneticVariation BEFREE The aim of this study was to determine the influence of rs1058587 SNP within GDF15(MIC1) gene on the risk of CVD in a Colombian RA population. 26090487 2015
dbSNP: rs1058587
rs1058587
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
CUI: C0007222
Disease:
Cardiovascular Diseases
0.010 GeneticVariation BEFREE GDF15 (rs1058587) does not influence the development of CVD in the population studied. 26090487 2015
dbSNP: rs4808793
rs4808793
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
CUI: C1956346
Disease:
Coronary Artery Disease
0.010 GeneticVariation BEFREE Logistic regression did not reveal any increased risk of CAD in subjects carrying the CG, GG genotype, or G allele at rs4808793</span> compared with individuals carrying the CC genotype or C allele; this finding was the same when subjects were grouped by sex (all P > 0.05). 21312063 2011