rs104893877, SNCA

N. diseases: 59
Disease: Movement Disorders ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Movement Disorders
CUI: C0026650
Disease: Movement Disorders
0.030 GeneticVariation BEFREE Mice overexpressing the human A53T mutant alpha-Syn develop a severe movement disorder, paralysis, and synucleinopathy, but the mechanisms are not understood. 16399671 2006
Movement Disorders
CUI: C0026650
Disease: Movement Disorders
0.030 GeneticVariation BEFREE Mice carrying an Ala53Thr human SNCA transgene driven by the mouse prion promoter show a mild movement disorder and only rarely develop severe pathology by 2 years of age. 15585343 2005
Movement Disorders
CUI: C0026650
Disease: Movement Disorders
0.030 GeneticVariation BEFREE Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. 12062037 2002