rs104894228, LRRC56;HRAS

N. diseases: 48
Disease: Thyroid Neoplasm ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Thyroid Neoplasm
CUI: C0040136
Disease: Thyroid Neoplasm
0.710 GeneticVariation BEFREE Here, we show that depletion of RAF-1, a RAF family member with a poorly defined role in TC, decreases proliferation and increases apoptosis in TPC-1 cells and, less significantly, in cells harboring a BRAF(V600E) or HRAS(G13R) mutations, but without affecting ERK activation. 26265449 2015
Thyroid Neoplasm
CUI: C0040136
Disease: Thyroid Neoplasm
0.710 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Thyroid Neoplasm
CUI: C0040136
Disease: Thyroid Neoplasm
0.710 CausalMutation CLINVAR Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer. 23406027 2013
Thyroid Neoplasm
CUI: C0040136
Disease: Thyroid Neoplasm
0.710 CausalMutation CLINVAR Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer. 23406027 2013
Thyroid Neoplasm
CUI: C0040136
Disease: Thyroid Neoplasm
0.710 CausalMutation CLINVAR Phase II trial of sorafenib in metastatic thyroid cancer. 19255327 2009
Thyroid Neoplasm
CUI: C0040136
Disease: Thyroid Neoplasm
0.710 CausalMutation CLINVAR Phase II trial of sorafenib in metastatic thyroid cancer. 19255327 2009
Thyroid Neoplasm
CUI: C0040136
Disease: Thyroid Neoplasm
0.710 CausalMutation CLINVAR Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma. 19773371 2009
Thyroid Neoplasm
CUI: C0040136
Disease: Thyroid Neoplasm
0.710 CausalMutation CLINVAR Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma. 19773371 2009
Thyroid Neoplasm
CUI: C0040136
Disease: Thyroid Neoplasm
0.710 CausalMutation CLINVAR Hyperactive Ras in developmental disorders and cancer. 17384584 2007
Thyroid Neoplasm
CUI: C0040136
Disease: Thyroid Neoplasm
0.710 CausalMutation CLINVAR Hyperactive Ras in developmental disorders and cancer. 17384584 2007