rs10490924, ARMS2;LOC105378525
N. diseases: 16
Source: ALL
| Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | GWASCAT | Genome-wide association study of neovascular age-related macular degeneration in the Thai population. | 28703135 | 2017 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | BEFREE | To compare the published results of studies on the genotype association of ARMS2/LOC387715 A69S, CFH Y402H, and CFH I62V in cases diagnosed as retinal angiomatous proliferation (RAP) versus neovascular age-related macular degeneration (AMD) or healthy controls. | 28005184 | 2017 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | BEFREE | In the subgroup with genotype data, ARMS2 rs10490924 and CFH rs800292 were associated with nAMD. | 28120909 | 2017 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | BEFREE | ARMS2 A69S polymorphism is associated with the number of ranibizumab injections needed for exudative age-related macular degeneration in a pro re nata regimen during 4 years of follow-up. | 28744656 | 2017 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | BEFREE | A study was undertaken to investigate the association between A69S in age-related maculopathy susceptibility 2 (ARMS2) and the response to anti-angiogenesis treatment in exudative age-related macular degeneration (AMD). | 25185256 | 2015 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | GWASCAT | New loci and coding variants confer risk for age-related macular degeneration in East Asians. | 25629512 | 2015 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | BEFREE | CFH Y402H and ARMS2 A69S Polymorphisms and Oral Supplementation with Docosahexaenoic Acid in Neovascular Age-Related Macular Degeneration Patients: The NAT2 Study. | 26132079 | 2015 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | BEFREE | After adjusting for rs11200638, ARMS2 rs10490924 remained significantly associated with nAMD and PCV (p<0.001). | 23326481 | 2013 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | GWASCAT | Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. | 22705344 | 2012 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | BEFREE | A69S and R38X ARMS2 and Y402H CFH gene polymorphisms as risk factors for neovascular age-related macular degeneration in Poland - a brief report. | 22293892 | 2012 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | BEFREE | To study the association of ARMS2 A69S genotype with the development of exudative age-related macular degeneration (AMD) in the unaffected fellow eye and to estimate the duration until the development of AMD in the second eye. | 22809783 | 2012 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | BEFREE | To investigate whether the A69S variant of the age-related maculopathy susceptibility 2 gene (ARMS2) has a different hereditary contribution in neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). | 22219653 | 2011 | |||||
Exudative age-related macular degeneration
|
0.800 | GeneticVariation | BEFREE | The polymorphisms responsible for nAMD and PCV may be located in this region or in the strong linkage disequilibrium of rs10490924 and rs11200638. | 21191724 | 2010 |