rs1049353, CNR1

N. diseases: 42
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Unipolar Depression
CUI: C0041696
Disease: Unipolar Depression
0.040 GeneticVariation BEFREE Haplotype frequency distributions between MD sample and controls showed a significant difference for Block 1 (rs806368-rs1049353-rs806371) (p = 0.008). 23407780 2013
Unipolar Depression
CUI: C0041696
Disease: Unipolar Depression
0.040 GeneticVariation BEFREE The rs1049353 polymorphism also buffered the effects of childhood physical abuse on major depressive disorder; however, this influence was largely attributable to anhedonic depression. 22393204 2012
Unipolar Depression
CUI: C0041696
Disease: Unipolar Depression
0.040 GeneticVariation BEFREE We assessed the CB1 receptor gene (CNR1) single nucleotide polymorphism (SNP) rs1049353 (1359 G/A) and the fatty acid amide hydrolase (FAAH) gene rs324420 SNP (cDNA 385C to A) for their associations with MD and/or BD in 83 Caucasian patients with recurrent MD, 134 Caucasian individuals with BD, and 117 Caucasian healthy subjects. 20080186 2010
Unipolar Depression
CUI: C0041696
Disease: Unipolar Depression
0.040 GeneticVariation BEFREE Therefore, the impact of cannabinoid receptor 1 gene (CNR1) variants rs1049353 and rs12720071 on antidepressant treatment response was evaluated in 256 Caucasian patients with Major Depression. 18579347 2008