rs1052133, OGG1;CAMK1

N. diseases: 147
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE This meta-analysis showed there was no association between hOGG1 rs1052133 and GC. 28415729 2017
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE Lack of association between the hOGG1 gene Ser326Cys polymorphism and gastric cancer risk: evidence from a case-control study and a meta-analysis. 26600527 2015
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE This meta-analysis provided evidence that hOGG1 S326C genetic polymorphism was not associated with increased risk of gastric cancer. 22296498 2012
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE To clarify any association between the hOGG1 Ser326Cys polymorphism and susceptibility to gastric cancer. 22799296 2012
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE Taken together, the results suggest that the hOGG1 Ser326Cys polymorphism may contribute to susceptibility to gastric cancer. 22343785 2012
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE Our result could explain the association between hOGG1 Ser326Cys polymorphism and GC risk. 22294108 2012
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE No significant association was found for either allele or genotype with gastric cancer (odds ratio [OR]=0.96; 95% confidence interval [95% CI]: 0.82-1.13; P=0.66), and this was also the case after combining 326Ser/Cys and 326Ser/Ser genotypes together (OR=0.87; 95% CI: 0.63-1.20; P=0.40), or 326Cys/Cys and 326Ser/Cys together (OR=1.03; 95% CI: 0.87-1.22; P=0.72). 22471492 2011
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE The significant effects of hOGG1 Ser326Cys polymorphism on colorectal, breast, bladder, prostate, esophageal, and gastric cancer were not detected. 22114677 2011
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE Although smokers and high salted tea drinkers themselves were at higher risk for gastric cancer (OR=8.975, P=0.0001; OR=14.778, P=0.0001), interaction with OGG1 Ser326Cys did not further modulate the risk. 20593951 2010
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), nucleotide excision repair (XPC-PAT, XPA-23G>A, ERCC1-19007T>C and XPD-L751Q), recombination (XRCC3-T241M) and alkylation damage reversal (MGMT-L84F) were tested for their potential role in the development of GC by using logistic regression models. 20817763 2010
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE To investigate the association between Ser326Cys human oxoguanine glycosylase 1 (hOGG1) polymorphism and atrophic gastritis and gastric cancer after Helicobacter pylori (H. pylori) eradication. 20845517 2010
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group 1 (XRCC1, Arg194Trp and Arg399Gln), adenosine diphosphate ribosyl transferase (ADPRT, Val762Ala), 8-oxoguanine DNA glycosylase (OGG1, Ser326Cys) and apurinic/apyrimidinic endonuclease 1 (APE1, Asp148Glu) and evolution of H.pylori-associated precancerous gastric lesions, a population-based cohort study was conducted in Linqu County, a high-risk area of gastric cancer in China. 19147860 2009
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in Japanese populations. 15596047 2004
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.100 GeneticVariation BEFREE We examined the distribution of the hOGG1 Ser326Cys polymorphism and its presumed correlation with gastric cancer risk in two case-control studies of different ethnic groups in São Paulo, Brazil. 11448535 2001