Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Among the results for 57 SNPs and 2 gene deletions, rs1056827 in CYP1B1, rs2959008 and rs7173655 in CYP11A1, the GSTT1 gene deletion, and rs1052133 in hOGG1 showed a statistically significant interaction with acrylamide intake for ER+ breast cancer risk.
|
29445914 |
2019 |
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This research aimed to study the associations between XPD (G751A, rs13181), hOGG1 (C326G, rs1052133) and XRCC4 (G1394T, rs6869366) gene polymorphisms and the risk of colorectal cancer (CRC) in a Chinese Han population.
|
30429230 |
2019 |
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
Using the multifactor dimensionality reduction method, we found a model of gene-gene interactions associated with the risk of lung cancer: NBS1 (rs1805794)-XRCC1 (rs25487)-hOGG1 (rs1052133)-XPG (rs17655).
|
31584889 |
2019 |
Carcinoma of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
To analyze the relationship of GSTT1, GSTM1, XRCC1 (rs25487), ERCC1 (rs11615, rs3212986), ERCC2 (rs13181), XRCC3 (rs861539), OGG1 (rs1052133), and Alpha-1-Antitrypsin mutations (AAT) with the risk of lung cancer in never-smokers, and ascertain if there is an effect modification between these polymorphisms and residential radon exposure.
|
31446980 |
2019 |
Malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
To analyze the relationship of GSTT1, GSTM1, XRCC1 (rs25487), ERCC1 (rs11615, rs3212986), ERCC2 (rs13181), XRCC3 (rs861539), OGG1 (rs1052133), and Alpha-1-Antitrypsin mutations (AAT) with the risk of lung cancer in never-smokers, and ascertain if there is an effect modification between these polymorphisms and residential radon exposure.
|
31446980 |
2019 |
Malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
Using the multifactor dimensionality reduction method, we found a model of gene-gene interactions associated with the risk of lung cancer: NBS1 (rs1805794)-XRCC1 (rs25487)-hOGG1 (rs1052133)-XPG (rs17655).
|
31584889 |
2019 |
Carcinoma of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
Using the multifactor dimensionality reduction method, we found a model of gene-gene interactions associated with the risk of lung cancer: NBS1 (rs1805794)-XRCC1 (rs25487)-hOGG1 (rs1052133)-XPG (rs17655).
|
31584889 |
2019 |
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
To analyze the relationship of GSTT1, GSTM1, XRCC1 (rs25487), ERCC1 (rs11615, rs3212986), ERCC2 (rs13181), XRCC3 (rs861539), OGG1 (rs1052133), and Alpha-1-Antitrypsin mutations (AAT) with the risk of lung cancer in never-smokers, and ascertain if there is an effect modification between these polymorphisms and residential radon exposure.
|
31446980 |
2019 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Among the results for 57 SNPs and 2 gene deletions, rs1056827 in CYP1B1, rs2959008 and rs7173655 in CYP11A1, the GSTT1 gene deletion, and rs1052133 in hOGG1 showed a statistically significant interaction with acrylamide intake for ER+ breast cancer risk.
|
29445914 |
2019 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
No significant associations were observed among rs1130409, rs1052133, rs2072668 and breast cancer risk.
|
29720094 |
2018 |
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
Effects of the Ser326Cys Polymorphism in the DNA Repair OGG1 Gene on Cancer, Cardiovascular, and All-Cause Mortality in the PREDIMED Study: Modulation by Diet.
|
29305130 |
2018 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
This study suggested that the carrier of Ser326Cys polymorphism of hOGG1, Cys/Cys vs Ser/Ser, are at higher risk for breast cancer, independent of other hormonal and environmental risk factors.
|
28608470 |
2018 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
In contrast to the CC and CG genotypes, the GG genotype of rs1052133 located on theOGG1 gene appeared to be a protective factor against developing breast cancer in both Mongoloid and Caucasoid populations.
|
29662639 |
2018 |
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
Effects of the Ser326Cys Polymorphism in the DNA Repair OGG1 Gene on Cancer, Cardiovascular, and All-Cause Mortality in the PREDIMED Study: Modulation by Diet.
|
29305130 |
2018 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In contrast to the CC and CG genotypes, the GG genotype of rs1052133 located on theOGG1 gene appeared to be a protective factor against developing breast cancer in both Mongoloid and Caucasoid populations.
|
29662639 |
2018 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This study suggested that the carrier of Ser326Cys polymorphism of hOGG1, Cys/Cys vs Ser/Ser, are at higher risk for breast cancer, independent of other hormonal and environmental risk factors.
|
28608470 |
2018 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
No significant associations were observed among rs1130409, rs1052133, rs2072668 and breast cancer risk.
|
29720094 |
2018 |
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
The 127 studies including 38,757 cancer patients and 50,177 control subjects were analyzed for the meta-analysis.Our meta-analysis revealed that G allele of Ser326Cys polymorphism of the hOGG1 gene statistically increased the susceptibility of cancer (all population, OR = 1.092, 95% CI = 1.051-1.134, p < 0.001; in Asian, OR = 1.095, 95% CI = 1.048-1.145, p < 0.001; in Caucasian, OR = 1.097, 95% CI = 1.033-1.179, p = 0.002).
|
28415770 |
2017 |
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
The 127 studies including 38,757 cancer patients and 50,177 control subjects were analyzed for the meta-analysis.Our meta-analysis revealed that G allele of Ser326Cys polymorphism of the hOGG1 gene statistically increased the susceptibility of cancer (all population, OR = 1.092, 95% CI = 1.051-1.134, p < 0.001; in Asian, OR = 1.095, 95% CI = 1.048-1.145, p < 0.001; in Caucasian, OR = 1.097, 95% CI = 1.033-1.179, p = 0.002).
|
28415770 |
2017 |
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our findings showed that hOGG1-Ser326Cys Cys allele is statistically important and relevant with respect to the development of oral squamous cancer.
|
28448977 |
2017 |
Stomach Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis showed there was no association between hOGG1 rs1052133 and GC.
|
28415729 |
2017 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
The hOGG1 SNP rs1052133 (Ser326Cys) minor allele T showed a significant association with breast cancer samples (OR = 1.78, χ2 = 7.86, p = 0.02024).
|
27822728 |
2017 |
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our findings showed that hOGG1-Ser326Cys Cys allele is statistically important and relevant with respect to the development of oral squamous cancer.
|
28448977 |
2017 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The hOGG1 SNP rs1052133 (Ser326Cys) minor allele T showed a significant association with breast cancer samples (OR = 1.78, χ2 = 7.86, p = 0.02024).
|
27822728 |
2017 |
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis showed there was no association between hOGG1 rs1052133 and GC.
|
28415729 |
2017 |