|
Colorectal Carcinoma
|
|
0.840 |
GeneticVariation
|
BEFREE |
Additionally, our GWAS confirmed the previously reported association with CRC of five SNPs located at 3q36.2 (rs10936599), 8q24 (rs10505477), 8q24.21(rs6983267), 11q13.4 (rs3824999) and 14q22.2 (rs4444235).
|
24978480 |
2014 |
|
Colorectal Carcinoma
|
|
0.840 |
GeneticVariation
|
BEFREE |
We found that 8 of 18 known CRC-associated SNPs (rs10936599, rs6983267, rs10795668, rs3802842, rs4444235, rs1957636, rs4939827, and rs961253) were over-represented in CRC-free patients with adenomas, compared with controls.
|
22999960 |
2013 |
|
Colorectal Carcinoma
|
|
0.840 |
GeneticVariation
|
BEFREE |
It was independently found that the same rs10936599 allele was associated with increased risk of both CRC and colorectal adenomas.
|
21708826 |
2012 |
|
Colorectal Carcinoma
|
|
0.840 |
GeneticVariation
|
GWASCAT |
We identified associations at four new CRC risk loci: 1q41 (rs6691170, odds ratio (OR) = 1.06, P = 9.55 × 10⁻¹⁰ and rs6687758, OR = 1.09, P = 2.27 × 10⁻⁹, 3q26.2 (rs10936599, OR = 0.93, P = 3.39 × 10⁻⁸), 12q13.13 (rs11169552, OR = 0.92, P = 1.89 × 10⁻¹⁰ and rs7136702, OR = 1.06, P = 4.02 × 10⁻⁸) and 20q13.33 (rs4925386, OR = 0.93, P = 1.89 × 10⁻¹⁰).
|
20972440 |
2010 |
|
Colorectal Carcinoma
|
|
0.840 |
GeneticVariation
|
GWASDB |
We identified associations at four new CRC risk loci: 1q41 (rs6691170, odds ratio (OR) = 1.06, P = 9.55 × 10⁻¹⁰ and rs6687758, OR = 1.09, P = 2.27 × 10⁻⁹, 3q26.2 (rs10936599, OR = 0.93, P = 3.39 × 10⁻⁸), 12q13.13 (rs11169552, OR = 0.92, P = 1.89 × 10⁻¹⁰ and rs7136702, OR = 1.06, P = 4.02 × 10⁻⁸) and 20q13.33 (rs4925386, OR = 0.93, P = 1.89 × 10⁻¹⁰).
|
20972440 |
2010 |
|
Colorectal Carcinoma
|
|
0.840 |
GeneticVariation
|
BEFREE |
We identified associations at four new CRC risk loci: 1q41 (rs6691170, odds ratio (OR) = 1.06, P = 9.55 × 10⁻¹⁰ and rs6687758, OR = 1.09, P = 2.27 × 10⁻⁹, 3q26.2 (rs10936599, OR = 0.93, P = 3.39 × 10⁻⁸), 12q13.13 (rs11169552, OR = 0.92, P = 1.89 × 10⁻¹⁰ and rs7136702, OR = 1.06, P = 4.02 × 10⁻⁸) and 20q13.33 (rs4925386, OR = 0.93, P = 1.89 × 10⁻¹⁰).
|
20972440 |
2010 |
|
Multiple Myeloma
|
|
0.810 |
GeneticVariation
|
BEFREE |
Common single-nucleotide polymorphisms (SNPs) at 2p23.3 (rs6746082), 3p22.1 (rs1052501), 3q26.2 (rs10936599), 6p21.33 (rs2285803), 7p15.3 (rs4487645), 17p11.2 (rs4273077), and 22q13.1 (rs877529) have recently been shown to influence MM risk.
|
24449210 |
2014 |
|
Multiple Myeloma
|
|
0.810 |
GeneticVariation
|
GWASDB |
Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.
|
23955597 |
2013 |
|
Multiple Myeloma
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.
|
23955597 |
2013 |
|
Chronic Lymphocytic Leukemia
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
|
24292274 |
2014 |
|
Chronic Lymphocytic Leukemia
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
|
24292274 |
2014 |
|
Multiple Sclerosis
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
|
21833088 |
2011 |
|
Multiple Sclerosis
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
|
21833088 |
2011 |
|
Celiac Disease
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Multiple common variants for celiac disease influencing immune gene expression.
|
20190752 |
2010 |
|
Celiac Disease
|
|
0.800 |
GeneticVariation
|
GWASDB |
Multiple common variants for celiac disease influencing immune gene expression.
|
20190752 |
2010 |
|
Malignant neoplasm of urinary bladder
|
|
0.720 |
GeneticVariation
|
BEFREE |
At the end of the study, we suggested that there may exist an association between a combination of MYNN rs10936599 and TERC rs2293607 polymorphisms and development of bladder cancer in Turkish population.
|
30120764 |
2019 |
|
Carcinoma of bladder
|
|
0.720 |
GeneticVariation
|
BEFREE |
At the end of the study, we suggested that there may exist an association between a combination of MYNN rs10936599 and TERC rs2293607 polymorphisms and development of bladder cancer in Turkish population.
|
30120764 |
2019 |
|
Malignant neoplasm of urinary bladder
|
|
0.720 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies multiple loci associated with bladder cancer risk.
|
24163127 |
2014 |
|
Malignant neoplasm of urinary bladder
|
|
0.720 |
GeneticVariation
|
BEFREE |
Overall, seven of the 14 variants were significantly associated with bladder cancer risk (p = 9.763 × 10(-3) for rs9642880 at 8q24.21, p = 3.004 × 10(-3) for rs2294008 at 8q24.3, p = 0.012 for rs798766 at 4p16.3, p = 0.034 for rs1495741 at 8p22, p = 2.306 × 10(-4) for GSTM1, p = 8.507 × 10(-8) for rs17674580 at 18q12.3, p = 7.179 × 10(-4) for rs10936599 at 3q26.2) and the odds ratios (ORs) ranged from 1.13 to 1.65.
|
24740636 |
2014 |
|
Carcinoma of bladder
|
|
0.720 |
GeneticVariation
|
BEFREE |
Overall, seven of the 14 variants were significantly associated with bladder cancer risk (p = 9.763 × 10(-3) for rs9642880 at 8q24.21, p = 3.004 × 10(-3) for rs2294008 at 8q24.3, p = 0.012 for rs798766 at 4p16.3, p = 0.034 for rs1495741 at 8p22, p = 2.306 × 10(-4) for GSTM1, p = 8.507 × 10(-8) for rs17674580 at 18q12.3, p = 7.179 × 10(-4) for rs10936599 at 3q26.2) and the odds ratios (ORs) ranged from 1.13 to 1.65.
|
24740636 |
2014 |
|
Carcinoma of bladder
|
|
0.720 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies multiple loci associated with bladder cancer risk.
|
24163127 |
2014 |
|
Small Lymphocytic Lymphoma
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
|
24292274 |
2014 |
|
Lung Diseases, Interstitial
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.
|
23583980 |
2013 |
|
Malignant tumor of colon
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.
|
20972440 |
2010 |
|
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.
|
20972440 |
2010 |