Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Neuroblastoma
CUI: C0027819
Disease: Neuroblastoma
0.850 GeneticVariation BEFREE Our findings revealed that rs110419 and rs2168101 polymorphisms were significantly associated with a decreased risk of NB in all genetic models. 31830377 2020
Neuroblastoma
CUI: C0027819
Disease: Neuroblastoma
0.850 GeneticVariation BEFREE <b>Results:</b> Significant associations with neuroblastoma risk were found for four (rs110419, rs4758051, rs10840002, and rs2168101) out of the five polymorphisms. 30406033 2018
Neuroblastoma
CUI: C0027819
Disease: Neuroblastoma
0.850 GeneticVariation BEFREE We also confirmed that rs6939340 A>G (G versus A: OR=1.30, 95% CI=1.13-1.50) and rs110419 G>A (A versus G: OR=1.37, 95% CI=1.19-1.58) were associated with increased neur</span>oblastoma risk for all subjects. 29024823 2017
Neuroblastoma
CUI: C0027819
Disease: Neuroblastoma
0.850 GeneticVariation BEFREE We found that the rs110419 A > G polymorphism was associated with a significantly decreased neuroblastoma</span> risk (AG vs. AA: adjusted OR = 0.65, 95% CI = 0.47-0.91; GG vs. AA: adjusted OR = 0.58, 95% CI = 0.36-0.91; AG/GG vs. AA: adjusted OR = 0.63, 95% CI = 0.46-0.86), and the protective effect was more predominant in children of age > 18 months, males, subgroups with tumor in adrenal gland and mediastinum, and patients in clinical stages III/IV. 27009839 2016
Neuroblastoma
CUI: C0027819
Disease: Neuroblastoma
0.850 GeneticVariation BEFREE A major haplotype, ATC, containing rs204926, rs110420, and rs110419, conferred a significant increase in risk for NB (OR = 1.82, 95% CI: 1.41-2.36, adjusted P < 0.001). 26030754 2015
Neuroblastoma
CUI: C0027819
Disease: Neuroblastoma
0.850 GeneticVariation GWASDB Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma. 22941191 2012
Neuroblastoma
CUI: C0027819
Disease: Neuroblastoma
0.850 GeneticVariation GWASCAT Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma. 22941191 2012
Neuroblastoma
CUI: C0027819
Disease: Neuroblastoma
0.850 GeneticVariation GWASCAT Integrative genomics identifies LMO1 as a neuroblastoma oncogene. 21124317 2011
Neuroblastoma
CUI: C0027819
Disease: Neuroblastoma
0.850 GeneticVariation GWASDB Integrative genomics identifies LMO1 as a neuroblastoma oncogene. 21124317 2011
Body Height
CUI: C0005890
Disease: Body Height
0.700 GeneticVariation GWASCAT Evaluation and application of summary statistic imputation to discover new height-associated loci. 29782485 2018
Diastolic blood pressure
CUI: C0428883
Disease: Diastolic blood pressure
0.700 GeneticVariation GWASCAT Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. 27618447 2016
Central neuroblastoma
CUI: C0700095
Disease: Central neuroblastoma
0.050 GeneticVariation BEFREE Our findings revealed that rs110419 and rs2168101 polymorphisms were significantly associated with a decreased risk of NB in all genetic models. 31830377 2020
Childhood Neuroblastoma
CUI: C4086165
Disease: Childhood Neuroblastoma
0.050 GeneticVariation BEFREE Our findings revealed that rs110419 and rs2168101 polymorphisms were significantly associated with a decreased risk of NB in all genetic models. 31830377 2020
Childhood Neuroblastoma
CUI: C4086165
Disease: Childhood Neuroblastoma
0.050 GeneticVariation BEFREE <b>Results:</b> Significant associations with neuroblastoma risk were found for four (rs110419, rs4758051, rs10840002, and rs2168101) out of the five polymorphisms. 30406033 2018
Central neuroblastoma
CUI: C0700095
Disease: Central neuroblastoma
0.050 GeneticVariation BEFREE <b>Results:</b> Significant associations with neuroblastoma risk were found for four (rs110419, rs4758051, rs10840002, and rs2168101) out of the five polymorphisms. 30406033 2018
Childhood Neuroblastoma
CUI: C4086165
Disease: Childhood Neuroblastoma
0.050 GeneticVariation BEFREE We also confirmed that rs6939340 A>G (G versus A: OR=1.30, 95% CI=1.13-1.50) and rs110419 G>A (A versus G: OR=1.37, 95% CI=1.19-1.58) were associated with increased neur</span>oblastoma risk for all subjects. 29024823 2017
Central neuroblastoma
CUI: C0700095
Disease: Central neuroblastoma
0.050 GeneticVariation BEFREE We also confirmed that rs6939340 A>G (G versus A: OR=1.30, 95% CI=1.13-1.50) and rs110419 G>A (A versus G: OR=1.37, 95% CI=1.19-1.58) were associated with increased neur</span>oblastoma risk for all subjects. 29024823 2017
Central neuroblastoma
CUI: C0700095
Disease: Central neuroblastoma
0.050 GeneticVariation BEFREE We found that the rs110419 A > G polymorphism was associated with a significantly decreased neuroblastoma</span> risk (AG vs. AA: adjusted OR = 0.65, 95% CI = 0.47-0.91; GG vs. AA: adjusted OR = 0.58, 95% CI = 0.36-0.91; AG/GG vs. AA: adjusted OR = 0.63, 95% CI = 0.46-0.86), and the protective effect was more predominant in children of age > 18 months, males, subgroups with tumor in adrenal gland and mediastinum, and patients in clinical stages III/IV. 27009839 2016
Childhood Neuroblastoma
CUI: C4086165
Disease: Childhood Neuroblastoma
0.050 GeneticVariation BEFREE We found that the rs110419 A > G polymorphism was associated with a significantly decreased neuroblastoma</span> risk (AG vs. AA: adjusted OR = 0.65, 95% CI = 0.47-0.91; GG vs. AA: adjusted OR = 0.58, 95% CI = 0.36-0.91; AG/GG vs. AA: adjusted OR = 0.63, 95% CI = 0.46-0.86), and the protective effect was more predominant in children of age > 18 months, males, subgroups with tumor in adrenal gland and mediastinum, and patients in clinical stages III/IV. 27009839 2016
Childhood Neuroblastoma
CUI: C4086165
Disease: Childhood Neuroblastoma
0.050 GeneticVariation BEFREE A major haplotype, ATC, containing rs204926, rs110420, and rs110419, conferred a significant increase in risk for NB (OR = 1.82, 95% CI: 1.41-2.36, adjusted P < 0.001). 26030754 2015
Central neuroblastoma
CUI: C0700095
Disease: Central neuroblastoma
0.050 GeneticVariation BEFREE A major haplotype, ATC, containing rs204926, rs110420, and rs110419, conferred a significant increase in risk for NB (OR = 1.82, 95% CI: 1.41-2.36, adjusted P < 0.001). 26030754 2015
Nephroblastoma
CUI: C0027708
Disease: Nephroblastoma
0.010 GeneticVariation BEFREE Only rs110419 AG was found to be protective against Wilms' tumor (adjusted OR = 0.62, 95% CI = 0.41-0.94, <i>P</i> = 0.024) when compared to rs110419 AA. 28881592 2017
Childhood Kidney Wilms Tumor
CUI: C1333015
Disease: Childhood Kidney Wilms Tumor
0.010 GeneticVariation BEFREE Only rs110419 AG was found to be protective against Wilms' tumor (adjusted OR = 0.62, 95% CI = 0.41-0.94, <i>P</i> = 0.024) when compared to rs110419 AA. 28881592 2017
Neoplasms
CUI: C0027651
Disease: Neoplasms
0.010 GeneticVariation BEFREE We found that the rs110419 A > G polymorphism was associated with a significantly decreased neuroblastoma risk (AG vs. AA: adjusted OR = 0.65, 95% CI = 0.47-0.91; GG vs. AA: adjusted OR = 0.58, 95% CI = 0.36-0.91; AG/GG vs. AA: adjusted OR = 0.63, 95% CI = 0.46-0.86), and the protective effect was more predominant in children of age > 18 months, males, subgroups with tumor in adrenal gland and mediastinum, and patients in clinical stages III/IV. 27009839 2016