rs11191548, CNNM2

N. diseases: 10
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.780 GeneticVariation GWASCAT Interethnic analyses of blood pressure loci in populations of East Asian and European descent. 30487518 2018
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.780 GeneticVariation BEFREE Associations of the hypertension-related single nucleotide polymorphism rs11191548 with high-density lipoprotein cholesterol and leptin in Chinese children. 29338791 2018
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.780 GeneticVariation BEFREE In conclusion, the rs11191548 CYP17A1 gene mutation was associated with hypertension and the serum 25(OH) D levels in Han Chinese. 29556032 2018
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.780 GeneticVariation BEFREE RESULTS The polymorphisms rs11191548 and rs4919687 were significantly associated with hypertension risk, which was confirmed by systolic and diastolic blood pressure distribution analyses between different genotype groups, and these two polymorphisms were found in linkage disequilibrium. 28537227 2017
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.780 GeneticVariation BEFREE The CYP17A1 polymorphism rs11191548 demonstrated a significant association with LVMI in patients with arterial hypertension and preserved LVEF. 26263970 2015
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.780 GeneticVariation BEFREE The present meta-analysis indicated significant associations of both CYP17A1 rs11191548 and FGF5 rs16998073 polymorphisms with hypertension susceptibility in East Asians. 22959498 2013
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.780 GeneticVariation BEFREE Conclusions The SNP rs11191548, near the CYP17A1 gene, was associated with hypertension and SBP in a Chinese Han population. 23467202 2013
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.780 GeneticVariation BEFREE We investigated the association of rs11191548 with hypertension in Chinese children. 22048715 2012
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.780 GeneticVariation BEFREE The genetic risk score, calculated as the sum of BP-increasing alleles of FGF5-rs16998073, CYP17A1-rs11191548, CYP17A1-rs1004467 and MTHFR-rs17367504, was significantly associated with increased SBP (1.16 mmHg/allele, P = 9.01E-5), DBP (0.51 mmHg/allele, P = 4.40E-4) and hypertension risk (OR = 1.22/allele, P = 2.74E-7). 20852445 2011