rs11556924, ZC3HC1

N. diseases: 21
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.840 GeneticVariation BEFREE In the present study, we aimed to examine the role of two single-nucleotide polymorphisms (SNPs), rs3825807 and rs11556924, located in the ADAMTS7 and ZC3HC1 genes, respectively, associated with CAD in published GWASs in European populations and their possible contribution to the development of coronary atherosclerosis and cerebral LA atherosclerosis in a case-control study of an the Iranian population. 31679296 2019
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.840 GeneticVariation GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.840 GeneticVariation GWASCAT Association analyses based on false discovery rate implicate new loci for coronary artery disease. 28714975 2017
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.840 GeneticVariation BEFREE These findings extend the genetic association between rs11556924 and coronary artery disease risk by characterizing its effects on the encoded protein, NIPA. 28115489 2017
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.840 GeneticVariation BEFREE The CAD-associated locus 7q32.2 is unusual in that the lead variant, rs11556924, is not in strong linkage disequilibrium with any other variant and introduces a coding change in ZC3HC1, which encodes NIPA. 27226629 2016
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.840 GeneticVariation GWASCAT A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. 26343387 2015
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.840 GeneticVariation GWASDB Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. 24262325 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.840 GeneticVariation BEFREE A recent meta-analysis has described the ZC3HC1 rs11556924 polymorphism as one of the most important signals associated with coronary artery disease (CAD) in non-rheumatic Caucasian individuals. 24286297 2013
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.810 GeneticVariation BEFREE These findings extend the genetic association between rs11556924 and coronary artery disease risk by characterizing its effects on the encoded protein, NIPA. 28115489 2017
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.810 GeneticVariation GWASCAT Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. 24262325 2014
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.810 GeneticVariation GWASDB A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. 22319020 2012
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.810 GeneticVariation GWASCAT Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. 21378990 2011
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.810 GeneticVariation GWASDB Large-scale gene-centric analysis identifies novel variants for coronary artery disease. 21966275 2011
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.810 GeneticVariation GWASDB Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. 21378990 2011
Age at menarche
CUI: C1314691
Disease: Age at menarche
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
Body Height
CUI: C0005890
Disease: Body Height
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
Red cell distribution width determination
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
Cardiovascular Diseases
CUI: C0007222
Disease: Cardiovascular Diseases
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
RDW - Red blood cell distribution width result
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
Diastolic blood pressure
CUI: C0428883
Disease: Diastolic blood pressure
0.700 GeneticVariation GWASCAT Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. 27841878 2017
Systolic Pressure
CUI: C0871470
Disease: Systolic Pressure
0.700 GeneticVariation GWASCAT The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. 27618452 2016
Platelet Count measurement
CUI: C0032181
Disease: Platelet Count measurement
0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
Blood basophil count (lab test)
CUI: C0200641
Disease: Blood basophil count (lab test)
0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
Diastolic blood pressure
CUI: C0428883
Disease: Diastolic blood pressure
0.700 GeneticVariation GWASCAT The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. 27618452 2016
Myocardial Infarction
CUI: C0027051
Disease: Myocardial Infarction
0.700 GeneticVariation GWASCAT A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. 26343387 2015