Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Squamous cell carcinoma
CUI: C0007137
Disease: Squamous cell carcinoma
0.720 GeneticVariation BEFREE Association of BRCA2 K3326* With Small Cell Lung Cancer and Squamous Cell Cancer of the Skin. 29767749 2018
Squamous cell carcinoma
CUI: C0007137
Disease: Squamous cell carcinoma
0.720 GeneticVariation BEFREE We analyzed the association between BRCA2 SNP rs11571833 and upper aerodigestive tract (UADT) cancer risk with multivariable unconditional logistic regression adjusted by sex and combinations of study and country for 5942 UADT squamous cell carcinoma case patients and 8086 control patients from nine different studies.All statistical tests were two-sided. rs11571833 was associated with UADT cancers (odds ratio = 2.53, 95% confidence interval = 1.89 to 3.38, P = 3x10(-10)) and was present in European, Latin American, and Indian populations but extremely rare in Japanese populations. 25838448 2015
Squamous cell carcinoma
CUI: C0007137
Disease: Squamous cell carcinoma
0.720 GeneticVariation GWASCAT Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. 24880342 2014