rs11591147, PCSK9
N. diseases: 28
Source: ALL
Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASCAT | Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. | 30670697 | 2019 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASCAT | Genetic analyses of diverse populations improves discovery for complex traits. | 31217584 | 2019 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASCAT | Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. | 30698716 | 2019 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASCAT | Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. | 30926973 | 2019 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASCAT | A large electronic-health-record-based genome-wide study of serum lipids. | 29507422 | 2018 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASCAT | Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. | 30275531 | 2018 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASCAT | The impact of low-frequency and rare variants on lipid levels. | 25961943 | 2015 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASCAT | Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. | 24507774 | 2014 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASDB | As expected, the minor allele of the PCSK9 R46L variant was in all cohorts associated with reduced PCSK9 levels and decreased plasma low-density lipoprotein-cholesterol concentrations, but no relationship was observed with the plasma triglyceride concentration. | 22460556 | 2012 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASDB | Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. | 23063622 | 2012 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASDB | Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project. | 22629316 | 2012 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASDB | Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. | 18193044 | 2008 | |||||
Low density lipoprotein cholesterol measurement
|
0.800 | GeneticVariation | GWASCAT | Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. | 18193044 | 2008 |