rs11651755, HNF1B

N. diseases: 9
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
0.800 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458 2018
Diabetes Mellitus, Non-Insulin-Dependent
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
0.800 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922 2012
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.710 GeneticVariation GWASCAT Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 28346442 2017
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.710 GeneticVariation BEFREE As rs11651755 in HNF1B modified both the ovarian cancer risk and also the risk for endometriosis, HNF1B may be causally involved in the pathogenetic pathway leading from endometriosis to ovarian cancer. 28214017 2017
Clear cell adenocarcinoma of ovary
CUI: C1518693
Disease: Clear cell adenocarcinoma of ovary
0.700 GeneticVariation GWASCAT Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 28346442 2017
Ovarian Serous Adenocarcinoma
CUI: C1335177
Disease: Ovarian Serous Adenocarcinoma
0.700 GeneticVariation GWASCAT Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 28346442 2017
Endometrial Carcinoma
CUI: C0476089
Disease: Endometrial Carcinoma
0.700 GeneticVariation GWASDB Genome-wide association study identifies a common variant associated with risk of endometrial cancer. 21499250 2011
Carcinoma, Ovarian Epithelial
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
0.020 GeneticVariation BEFREE As rs11651755 in HNF1B modified both the ovarian cancer risk and also the risk for endometriosis, HNF1B may be causally involved in the pathogenetic pathway leading from endometriosis to ovarian cancer. 28214017 2017
Carcinoma, Ovarian Epithelial
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
0.020 GeneticVariation BEFREE Different single-nucleotide polymorphisms associate with invasive serous (rs7405776 odds ratio (OR)=1.13, P=3.1 × 10(-10)) and clear cell (rs11651755 OR=0.77, P=1.6 × 10(-8)) epithelial ovarian cancer. 23535649 2013
Malignant neoplasm of ovary
CUI: C1140680
Disease: Malignant neoplasm of ovary
0.010 GeneticVariation BEFREE As rs11651755 in HNF1B modified both the ovarian cancer risk and also the risk for endometriosis, HNF1B may be causally involved in the pathogenetic pathway leading from endometriosis to ovarian cancer. 28214017 2017
Endometriosis
CUI: C0014175
Disease: Endometriosis
0.010 GeneticVariation BEFREE As rs11651755 in HNF1B modified both the ovarian cancer risk and also the risk for endometriosis, HNF1B may be causally involved in the pathogenetic pathway leading from endometriosis to ovarian cancer. 28214017 2017
Epithelial ovarian cancer
CUI: C0677886
Disease: Epithelial ovarian cancer
0.010 GeneticVariation BEFREE Different single-nucleotide polymorphisms associate with invasive serous (rs7405776 odds ratio (OR)=1.13, P=3.1 × 10(-10)) and clear cell (rs11651755 OR=0.77, P=1.6 × 10(-8)) epithelial ovarian cancer. 23535649 2013