|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our meta-analysis establishes that the MTHFR 677C>T polymorphism as a high-penetrant risk factor for VC in SCD patients.
|
30686687 |
2019 |
|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
We investigated <i>MTHFR</i> C677T polymorphism in SCD patients and found that the distribution of <i>MTHFR</i> C677T genotypes was significantly different between SCD patients and age-matched controls.
|
30687218 |
2018 |
|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
This work aimed at studying a possible influence of methylenetetrahydrofolate reductase (MTHFR; c. 677C>T) and cystathionine β-synthase (CBS; 844ins68) polymorphisms on overall oxidative status of sickle cell anemia (SCA) patients and on routine markers, correlating them with hydroxycarbamide (HC) treatment.
|
28188925 |
2017 |
|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
The Prevalence of Factor V Leiden (G1691A) and Methylenetetrahydrofolate Reductase C677T Mutations in Sickle Cell Disease in Western India.
|
23869056 |
2015 |
|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
MTHFR C677T and FVL G1691A polymorphisms may be risk factors for increased vascular complications in patient with SCD.
|
23992124 |
2013 |
|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
MTHFR polymorphic variant C677T is associated to vascular complications in sickle-cell disease.
|
22924497 |
2012 |
|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, MTHFR C677T polymorphism might be a risk factor for vascular complications in SCD.
|
16906320 |
2006 |
|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
Factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations among patients with sickle cell disease in Eastern Saudi Arabia.
|
15224376 |
2004 |
|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
Fasting and postmethionine load (PML) homocysteine, red cell folate, and the MTHFR C677T mutation were determined in 77 patients with SCD and 110 African-American controls.
|
12142786 |
2002 |
|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
The methylenetetrahydrofolate reductase gene C677T polymorphism in patients with homozygous sickle cell disease and stroke.
|
10583261 |
1999 |
|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
The prevalence of homozygosity for the C677T MTHFR variant was 5% in the patients with SCD.
|
10524453 |
1999 |
|
Anemia, Sickle Cell
|
|
0.100 |
GeneticVariation
|
BEFREE |
The prevalence of the prothrombin gene variant (allele 20.210 A), factor V Leiden mutation, and homozygosity for transition 677C-->T in the methylenetetrahydrofolate reductase (MTHFR) gene was determined among patients with sickle cell disease (SCD).
|
9723576 |
1998 |