|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
There was no difference in the distribution of the <i>MTHFR</i> 677C>T polymorphism between individuals with NW and overweight/obesity; neither when they were divided by overweight vs NW, nor when we contrasted obese vs NW.
|
31496910 |
2019 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
DNA was extracted from the whole blood of 192 natural postmenopausal women (40 to 65 years) screened for the METS and tested for three gene SNPs related to obesity: the fat mass obesity (FTO: rs9939609) and the methylenetetrahydrofolate reductase (MTHFR: C677T and A1298C).
|
26902996 |
2016 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Additive Interaction of MTHFR C677T and MTRR A66G Polymorphisms with Being Overweight/Obesity on the Risk of Type 2 Diabetes.
|
27983710 |
2016 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Interaction between the MTHFR C677T polymorphism and overweight/obesity on serum triglyceride levels, and interaction between the MTRR A66G polymorphism and overweight/obesity on serum high-density lipoprotein cholesterol levels were detected in women (P = 0.015 and P = 0.056, respectively).
|
27793164 |
2016 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Among them age, sex, tobacco use, alcohol consumption, and being overweight/obesity are well documented environmental determinants, and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is nominated as a potential genetic candidate.
|
27322299 |
2016 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
In our case-control study, the MTHFR C677T polymorphism was not significantly associated with being overweight/obesity when examining homozygous codominant, heterozygous codominant, dominant, recessive and allelic genetic models.
|
26016497 |
2015 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
The prevalence of hypertension (P < .001), smoking (P < .001), decreased HDL cholesterol levels (P < .001), obesity (P = .001), elevated LDL cholesterol (P = .036), C677T MTHFR polymorphism (P < .001), and genetic sum was significantly higher in the group of stroke patients.
|
24189452 |
2014 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
The aim of this study is to investigate whether methylenetetrahydrofolate reductase (MTHFR) C677T mutation is associated with the development of hyperlipoproteinemia and obesity in coronary heart disease (CHD).
|
24218123 |
2013 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
To examine the association between MTHFR gene C677T polymorphism in diabetes and obesity with serum homocysteine levels.
|
19437140 |
2010 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
The methylenetetrahydrofolate reductase C677T genotype and the risk of obesity in three large population-based cohorts.
|
18426813 |
2008 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
We evaluated the relationship between polymorphisms of methylene-tetrahydrofolate reductase (MTHFR C677T and A1298C), methionine synthase (MTR A2756G), methionine synthase reductase (MTRR A66G), betaine:homocysteine methyltransferase (BHMT G742A) and cystathionine beta-synthase (CBS 68-bp ins) genes and the risk of obesity.
|
17993766 |
2007 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Normal Weight Obese syndrome: role of single nucleotide polymorphism of IL-1 5Ralpha and MTHFR 677C-->T genes in the relationship between body composition and resting metabolic rate.
|
17121316 |
2006 |