rs121913279, PIK3CA

N. diseases: 101
Disease: Malignant neoplasm of ovary ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of ovary
CUI: C1140680
Disease: Malignant neoplasm of ovary
0.710 GeneticVariation BEFREE We also found that an activating (E545K) Pik3ca mutation, unlike Pten inactivation or Pik3ca H1047R mutation, cannot cooperate with Arid1a loss to promote ovarian cancer development in the mouse. 26279473 2016
Malignant neoplasm of ovary
CUI: C1140680
Disease: Malignant neoplasm of ovary
0.710 GeneticVariation UNIPROT Mutation of the PIK3CA gene in ovarian and breast cancer. 15520168 2004