rs121913483, FGFR3

N. diseases: 31
Disease: Carcinoma of bladder ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.720 GeneticVariation BEFREE PATIENT SUMMARY: We propose that APOBEC-mediated mutagenesis can generate clinically relevant driver mutations even within suboptimal motifs, such as in the case of FGFR3 S249C, one of the most common mutations in bladder cancer. 30975452 2019
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.720 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.720 GeneticVariation CLINVAR Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. 19381019 2009
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.720 GeneticVariation BEFREE Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer. 17384684 2007