High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
|
30275531 |
2018 |
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Discovery and refinement of loci associated with lipid levels.
|
24097068 |
2013 |
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Discovery and refinement of loci associated with lipid levels.
|
24097068 |
2013 |
Hypertensive disease
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
21909115 |
2011 |
Hypertensive disease
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
21909115 |
2011 |
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Biological, clinical and population relevance of 95 loci for blood lipids.
|
20686565 |
2010 |
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Biological, clinical and population relevance of 95 loci for blood lipids.
|
20686565 |
2010 |
Schizophrenia
|
|
0.750 |
GeneticVariation
|
BEFREE |
A nonsynonymous genetic variant (minor T allele of rs13107325 in SLC39A8, a gene implicated in schizophrenia) was associated with greater gray matter volume of the putamen (variance explained of 4.21% in the left hemisphere; 8.66; 95% CI, 6.59-10.81; P = 5.35 × 10-18; and 4.44% in the right hemisphere; t = 8.90; 95% CI, 6.75-11.19; P = 6.80 × 10-19) and also with a lower gene expression of SLC39A8 specifically in the putamen (t127 = -3.87; P = 1.70 × 10-4).
|
30649180 |
2019 |
Schizophrenia
|
|
0.750 |
GeneticVariation
|
BEFREE |
Multiple previous studies found that one of the most pleiotropic single nucleotide polymorphisms (SNPs) in SLC39A8, rs13107325, is associated with schizophrenia in the European population.
|
31533672 |
2019 |
Schizophrenia
|
|
0.750 |
GeneticVariation
|
BEFREE |
This manuscript presents arguments in favor of the rs13107325 variant as the functional variant responsible for the association of this locus with schizophrenia, reviews the genetic associations with this gene, the evidences of natural selection on the gene, and the known aspects about its structure and physiological functions.
|
28557351 |
2018 |
Schizophrenia
|
|
0.750 |
GeneticVariation
|
GWASCAT |
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
|
29483656 |
2018 |
Schizophrenia
|
|
0.750 |
GeneticVariation
|
BEFREE |
Here, we studied the evolutionary pattern of a schizophrenia risk variant rs13107325 (P < 5.0 × 10(-8) in Europeans) in the SLC39A8 gene.
|
26006263 |
2016 |
Schizophrenia
|
|
0.750 |
GeneticVariation
|
BEFREE |
Several loci are associated with multiple phenotypes; for example, a nonsynonymous variant in the zinc transporter SLC39A8 influences seven of the traits, including risk of schizophrenia (rs13107325: log-transformed odds ratio (log OR) = 0.15, P = 2 × 10(-12)) and Parkinson disease (log OR = -0.15, P = 1.6 × 10(-7)), among others.
|
27182965 |
2016 |
Schizophrenia
|
|
0.750 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of schizophrenia in Ashkenazi Jews.
|
26198764 |
2015 |
Intelligence
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.
|
29326435 |
2019 |
Body mass index
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Alcohol-Induced Disorders
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
|
30940813 |
2019 |
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
|
30578418 |
2019 |
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
|
30578418 |
2019 |
body fat percentage (physical finding)
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.
|
30593698 |
2019 |
Eczema
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Red Blood Cell Count measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Duration of sleep
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.
|
30846698 |
2019 |