rs1333049, CDKN2B-AS1

N. diseases: 60
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE ANRIL polymorphisms (rs1333049 and rs3217992) in relation to plasma CRP levels among in-patients with CHD. 31770616 2020
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE Further subgroup analyses showed that rs1333040, rs1333049 and rs2383207 polymorphisms were significantly correlated with the risk of CAD in East Asians, rs2383206 and rs10757274 polymorphisms were significantly correlated with the risk of CAD in West Asians, while rs2383206, rs10757274 and rs10757278 polymorphisms were significantly correlated with the risk of CAD in Caucasians. 30814313 2019
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE We genotyped the CAD-associated variants at the LPA (rs10455872) and 9p21 loci (rs1333049) in the GeneCAST (Genetics of Calcific Aortic STenosis) Consortium and conducted a meta-analysis for their association with AVS. 30482443 2019
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE Pooled overall analyses showed that rs1333040 (dominant model: P < 0.0001; recessive model: P < 0.0001; allele model: P < 0.0001), rs1333049 (dominant model: P = 0.02; allele model: P = 0.02) and rs2383207 (additive model: P = 0.004; allele model: P = 0.03) polymorphisms were significantly associated with the likelihood of CAD. 30387168 2019
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Gender-based subgroup tests showed that four polymorphisms (rs75227345, rs2383205, rs10738606 and rs1333049) were associated with CHD in males (p < .05). 31496134 2019
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE The polymorphic variants of Apo-A5; rs2266788 (C), 9p21.3; rs1333049 (C) rs2383207 (A) are associated with CAD, its severity and exerts the risk of MI in North Indian population. 29309886 2018
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation GWASCAT Genome-Wide Association and Functional Studies Identify SCML4 and THSD7A as Novel Susceptibility Genes for Coronary Artery Disease. 29472232 2018
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Association Study Between Coronary Artery Disease and rs1333049 Polymorphism at 9p21.3 Locus in Italian Population. 28639227 2017
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE Association Study Between Coronary Artery Disease and rs1333049 Polymorphism at 9p21.3 Locus in Italian Population. 28639227 2017
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Our study aims to explore the association of rs7025486 single-nucleotide polymorphisms (SNP) in DAB2IP and rs1333049 on chromosome 9p21.3 with the coronary artery disease in Chinese population. 28962556 2017
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE Our study aims to explore the association of rs7025486 single-nucleotide polymorphisms (SNP) in DAB2IP and rs1333049 on chromosome 9p21.3 with the coronary artery disease in Chinese population. 28962556 2017
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247 2016
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE We examined the prognostic values of the rs9508025 and rs1333049 variants that were found to be associated with coronary artery disease (CAD) risk in a previous Korean genome-wide association study. 27736948 2016
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Despite excellent power, the 9p21 locus SNP (rs1333049) was only modestly associated with MI (HR = 1.09, p-value = 0.02) and marginally with CHD (HR = 1.06, p-value = 0.08). 26950853 2016
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE The leading coronary artery disease-associated SNP rs1333049 was associated with coronary artery disease; however, none of the 9p21 SNP evaluated in the present study were associated with extreme longevity. 25257646 2015
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE The rs2383207 and rs1333049 SNPs on 9p21 chromosome were significantly associated with the risk and severity of CAD in the Turkish population. 25333979 2015
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE The leading coronary artery disease-associated SNP rs1333049 was associated with coronary artery disease; however, none of the 9p21 SNP evaluated in the present study were associated with extreme longevity. 25257646 2015
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE This study confirms the association between 9p21 (rs1333049) and fatal CHD in a Norwegian population-based cohort. 24728607 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE Higher FRS and PWV and the presence of rs2943634 risk allele were independent predictors of CAD (Nagelkerke R(2) 0·252, P < 0·001), while higher FRS and the presence of rs1333049 risk allele were independent predictors of multivessel CAD (Nagelkerke R(2) 0·190, P < 0·001). 24942486 2014
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Our case-control study and meta-analysis suggest that rs1333049 is a useful risk marker of CHD. 24930384 2014
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASCAT Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. 24262325 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE 849 CAD patients undergoing revascularization (660 with CAC and 189 without CAC) were enrolled in a cohort study to test its association with cardiovascular events in CAD patients with and without CAC in a 3-year follow-up. rs1333049 was significantly associated with the incidence of cardiovascular events in non-target vessels in patients with CAC (hazard ratio = 1.44, 95%CI, 1.08-1.91, P = 0.012), but not in those without CAC. 24732910 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation GWASDB Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. 24262325 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.900 GeneticVariation BEFREE A replication study and a meta-analysis of the association between the CDKN2A rs1333049 polymorphism and coronary heart disease. 24930384 2014