Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Prostate cancer, familial
CUI: C2931456
Disease: Prostate cancer, familial
0.060 GeneticVariation BEFREE A rare recurrent missense variant in HOXB13 (rs138213197/G84E) was recently reported to be associated with hereditary prostate cancer. 25595936 2015
Prostate cancer, familial
CUI: C2931456
Disease: Prostate cancer, familial
0.060 GeneticVariation BEFREE Men with the HOXB13 G84E variant had a 4.51-fold higher relative risk of PCa compared with non-carriers (95 % CI 3.28-6.20). 24026887 2014
Prostate cancer, familial
CUI: C2931456
Disease: Prostate cancer, familial
0.060 GeneticVariation BEFREE A rare but recurrent missense mutation (G84E, rs138213197) in the gene homeobox B13 (HOXB13) was recently reported to be associated with hereditary prostate cancer. 22841674 2014
Prostate cancer, familial
CUI: C2931456
Disease: Prostate cancer, familial
0.060 GeneticVariation BEFREE Recent genetic epidemiologic studies identified a germline mutation in the homeobox transcription factor, HOXB13 G84E, which is associated with markedly increased risk for prostate cancer, particularly early-onset hereditary prostate cancer. 24722062 2014
Prostate cancer, familial
CUI: C2931456
Disease: Prostate cancer, familial
0.060 GeneticVariation BEFREE The novel HOXB13 G84E variant is associated with a significantly increased risk of hereditary prostate cancer. 22236224 2012
Prostate cancer, familial
CUI: C2931456
Disease: Prostate cancer, familial
0.060 GeneticVariation BEFREE We evaluated the G84E germline mutation (rs138213197) of HOXB13 in a case-control study of familial prostate cancer at Vanderbilt University (Nashville, TN) to independently evaluate the association of the mutation with familial prostate cancer. 22714738 2012