rs147001633, DNMT3A

N. diseases: 15
Disease: Neoplasm, Residual ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Neoplasm, Residual
CUI: C0242596
Disease: Neoplasm, Residual
0.030 GeneticVariation BEFREE In addition to WT1 overexpression, other MRD positive markers were: NPM1 (Type A, B, K), DNMT3A (R882H), MLL-PTD, IDH1 (R132H) and KRAS (G12S). 30457973 2019
Neoplasm, Residual
CUI: C0242596
Disease: Neoplasm, Residual
0.030 GeneticVariation BEFREE We investigated the prognostic impact of minimal residual disease (MRD) monitoring in acute myeloid leukemia patients harboring DNA methyltransferase 3A-R882H/-R882C mutations (DNMT3A<sup>mut</sup>). 28643785 2018
Neoplasm, Residual
CUI: C0242596
Disease: Neoplasm, Residual
0.030 GeneticVariation BEFREE We identified 24 DNMT3A R882H mutated patients out of 134 acute myeloid leukemia screened samples and we analyzed in these patients the kinetics of minimal residual disease after induction and consolidation therapy. 25554589 2015