rs16969968, CHRNA5

N. diseases: 37
Disease: Cocaine Dependence ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Cocaine Dependence
CUI: C0600427
Disease: Cocaine Dependence
0.020 GeneticVariation BEFREE We replicated several previous findings, including associations between rs16969968 and nicotine dependence (P=0.002) and cocaine dependence (P=0.02), with opposite risk alleles for each substance. 20485328 2010
Cocaine Dependence
CUI: C0600427
Disease: Cocaine Dependence
0.020 GeneticVariation BEFREE The minor (A) allele of rs16969968, relative to the major G allele, appears to be both a risk factor for nicotine dependence and a protective factor for cocaine dependence. 18519132 2008