rs1799782, XRCC1

N. diseases: 151
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.080 GeneticVariation BEFREE APEX1 rs3136817, MUTYH rs3219493, three SNPs (rs3213356, rs25487 and rs1799782) in XRCC1, and three SNPs (rs1799794, rs861531 and rs861530) in XRCC3 showed significant associations with the risk of bladder cancer. 27153553 2016
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.080 GeneticVariation BEFREE This meta-analysis suggested that XRCC1 Arg194Trp and Arg280His polymorphisms were risk factors for increasing bladder cancer in Asian population. 24266849 2013
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.080 GeneticVariation BEFREE Our meta-analysis results suggest that XRCC1 Arg194Trp and Arg280His polymorphisms are associated with significantly increased risk of bladder cancer in Asians. 23636799 2013
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.080 GeneticVariation BEFREE The meta-analysis results suggest that XRCC1 Arg194Trp and Arg399Gln polymorphisms may be associated with elevated bladder cancer risk. 23496911 2013
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.080 GeneticVariation BEFREE Our meta-analysis shows that XRCC1 Arg194Trp and Arg280His polymorphisms are associated with a significantly increased risk of bladder cancer in Asian population. 23704969 2013
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.080 GeneticVariation BEFREE However, the XRCC1 R194W and R280H polymorphisms were both associated with increased bladder cancer risk among Asians. 24039945 2013
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.080 GeneticVariation BEFREE For Arg(194)Trp (six studies, 3091 cases, 3219 controls), no evidence indicated that individuals carrying the variant genotypes (Trp/Trp + Arg/Trp), relative to those carrying the wild homozygote Arg/Arg genotype, had a decreased risk of bladder cancer (odds ratio [OR] 0.90, 95% confidence interval [CI] 0.77 to 1.05; P = 0.17). 18336890 2008
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.080 GeneticVariation BEFREE It indicated that XRCC1 R399Q and R194W might not be risk factors to bladder cancer, but the 399QQ genotype decreased susceptibility of bladder cancer under recessive model and homozygote contrast among ever-smokers. 18765423 2008