rs1799782, XRCC1

N. diseases: 151
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.050 GeneticVariation BEFREE Taken together, there was no obvious association between the Arg194Trp or Arg280His polymorphism and cervical cancer risk. 27903984 2017
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.050 GeneticVariation BEFREE This meta-analysis provides strongly statistical evidence for the association between rs1799782 and cervical cancer risk, as well as its association with rs25487 only in Asian populations. 24057881 2014
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.050 GeneticVariation BEFREE The Arg194Trp polymorphism of XRCC1 increases risk of cervical cancer; the variant 399Gln allele predicts poor response to platinum-based chemotherapy, while the Arg194Trp polymorphism indicates a good response. 23464469 2012
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.050 GeneticVariation BEFREE This meta-analysis suggests that Arg194Trp polymorphism may be associated with CC risk, Arg399Gln polymorphism might be a low-penetrent risk factor for CC only in Asians, and there may be no association between Arg280His polymorphism and CC risk. 22984511 2012
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.050 GeneticVariation BEFREE The genotypes of XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine were associated with the response to NAC in patients with cervical cancer. 18851872 2008