|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
We identified 5 studies for Ala54Thr association with obesity in Asian subjects.
|
26238699 |
2015 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
The FABP2 Ala54Thr polymorphism was significantly associated with obesity (AT vs AA: OR = 2.633, 95%CI = 1.065-6.663, P = 0.036; TT vs AA: OR = 4.160, 95%CI = 1.609-10.757, P = 0.003) and metabolic syndrome (TT vs AA: OR = 2.273, 95%CI = 1.242-4.156, P = 0.008) by logistic regression with adjustment for covariates.
|
25730055 |
2015 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
To analyze the effect of the fatty acid-binding protein (FABP2) gene Ala54Thr polymorphism on anthropometric and biochemical variables in response to a moderate-fat diet in overweight or obese subjects.
|
22817827 |
2013 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
FABP2 A54T polymorphism may help identify Caucasian subjects at risk for obesity.
|
19324445 |
2009 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Influence of ALA54THR polymorphism of fatty acid-binding protein 2 on obesity and cardiovascular risk factors.
|
17992640 |
2007 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
The Ala54Thr polymorphism was not associated with type 2 diabetes mellitus or obesity.
|
16919542 |
2006 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
The aim of this study was to assess the frequency of fatty acid binding protein 2 (FABP2) Ala54Thr genetic polymorphism and to evaluate its association with obesity and insulin resistance in Chilean aboriginal populations.
|
17211557 |
2006 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort.
|
16718632 |
2006 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our results suggest that the Ala54Thr polymorphism of the FABP2 gene is associated with obesity and insulin resistance.
|
14981227 |
2004 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our data suggested that Ala54Thr polymorphism of the FABP2 gene is not a major contributing factor for obesity and obesity with dyslipidemia in Japanese children.
|
11866034 |
2001 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
A missense mutation (A54T) in the fatty acid binding protein type 2 (FABP2) gene has been associated with insulin resistance and obesity.
|
11707533 |
2001 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
(1) The Ala54 and Thr54 allele frequencies in Chinese were 0.71 and 0.29 respectively; (2) The FABP2-Ala54Thr variation was neither associated with fasting and post-challenged plasma glucose levels nor with NIDDM; (3) This variation was neither associated with fasting lipid profile nor with obesity; (4) The IGT subjects with genotype Thr54(+) (Thr54 homozygotes and heterozygotes) had lower fasting, 2-hour and total C-peptide levels and smaller AUC representing lesser C-peptide secretion after glucose challenge than those with genotype Thr54(-) (Ala54 homozygotes) (P = 0.04, 0.03, 0.01 and 0.01 respectively).
|
11593593 |
1999 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
An alanine to threonine substitution at codon 54 of the fatty acid binding protein 2 (FABP2) gene has been associated with insulin resistance in Pima Indians and with obesity in aboriginal Canadians.
|
10337870 |
1999 |