Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Renal sclerosis with hypertension
CUI: C0264657
Disease: Renal sclerosis with hypertension
0.010 GeneticVariation BEFREE We analyzed 821 subjects with hypertensive nephrosclerosis from the longitudinal National Institute of Diabetes and Digestive and Kidney Diseases African-American Study of Kidney Disease and Hypertension (AASK) Trial to determine whether decline in glomerular filtration rate (GFR) over ∼4.2 years was predicted by common genetic variation within MTHFR at non-synonymous positions C677T (Ala222Val) and A1298C (Glu429Ala) or by MTHFR haplotypes. 21613384 2012