rs1801483, GCGR

N. diseases: 7
Disease: Hypertensive disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.030 GeneticVariation BEFREE We conclude that the Gly40Ser polymorphism of the GCGR gene is associated with higher risk of hypertension and with enhanced proximal tubular sodium reabsorption, a factor possibly contributing to hypertension in this group. 11692154 2001
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.030 GeneticVariation BEFREE The Gly40Ser polymorphism was not significantly associated with hypertension in the whole study population, although the frequency of 40Ser carriers in hypertensive subjects was double that in normotensive subjects (3.1% in hypertensives versus 1.5%; P=0.087). 10406817 1999
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.030 GeneticVariation BEFREE No association of the Gly40Ser variant with hypertension was seen in this large population. 9325468 1997