melanoma
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.
|
28212542 |
2017 |
melanoma
|
|
0.810 |
GeneticVariation
|
BEFREE |
Finally, rs1801516, located on the ATM gene, showed a trend towards a protective role in MM similar to the one firstly described in a GWAS study.
|
23537197 |
2013 |
melanoma
|
|
0.810 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies three new melanoma susceptibility loci.
|
21983787 |
2011 |
melanoma
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies three new melanoma susceptibility loci.
|
21983787 |
2011 |
Plexiform leiomyoma
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits.
|
30194396 |
2018 |
Uterine Fibroids
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits.
|
30194396 |
2018 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
These results do not support an impact of ATM rs1801516 on late skin reactions of radiotherapy for breast cancer, nevertheless further large studies are still required for conclusive evidences.
|
31756226 |
2019 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
These results do not support an impact of ATM rs1801516 on late skin reactions of radiotherapy for breast cancer, nevertheless further large studies are still required for conclusive evidences.
|
31756226 |
2019 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Five variants were previously reported to confer risk of various malignant or benign tumors (rs78378222 in TP53, rs10069690 in TERT, rs1800057 and rs1801516 in ATM, and rs7907606 at OBFC1) and four signals are located at established risk loci for hormone-related traits (endometriosis and breast cancer) at 1q36.12 (CDC42/WNT4), 2p25.1 (GREB1), 20p12.3 (MCM8), and 6q26.2 (SYNE1/ESR1).
|
30194396 |
2018 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Five variants were previously reported to confer risk of various malignant or benign tumors (rs78378222 in TP53, rs10069690 in TERT, rs1800057 and rs1801516 in ATM, and rs7907606 at OBFC1) and four signals are located at established risk loci for hormone-related traits (endometriosis and breast cancer) at 1q36.12 (CDC42/WNT4), 2p25.1 (GREB1), 20p12.3 (MCM8), and 6q26.2 (SYNE1/ESR1).
|
30194396 |
2018 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Four SNPs [rs3218550 (XRCC2), rs6917 (PHB), rs1801516 (ATM), and rs13689 (CDH1)] were significantly associated with risk of breast cancer.
|
29433565 |
2018 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
After adjustment, rs189037 and rs1801516 were significantly associated with breast cancer under the additive model (OR: 1.37 and 1.52, 95% CI: 1.10-1.71 and 1.14-2.04, P: .005 and .005, respectively).
|
29691986 |
2018 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
After adjustment, rs189037 and rs1801516 were significantly associated with breast cancer under the additive model (OR: 1.37 and 1.52, 95% CI: 1.10-1.71 and 1.14-2.04, P: .005 and .005, respectively).
|
29691986 |
2018 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Four SNPs [rs3218550 (XRCC2), rs6917 (PHB), rs1801516 (ATM), and rs13689 (CDH1)] were significantly associated with risk of breast cancer.
|
29433565 |
2018 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
ATM polymorphisms IVS24-9delT, IVS38-8T>C, and 5557G>A in Mexican women with familial and/or early-onset breast cancer.
|
25014427 |
2014 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
ATM polymorphisms IVS24-9delT, IVS38-8T>C, and 5557G>A in Mexican women with familial and/or early-onset breast cancer.
|
25014427 |
2014 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In summary, the meta-analysis suggest that ATM 5557G>A polymorphism is associated with increased breast cancer risk among Amerindians.
|
21603857 |
2012 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
In summary, the meta-analysis suggest that ATM 5557G>A polymorphism is associated with increased breast cancer risk among Amerindians.
|
21603857 |
2012 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Importance of ATM gene as a susceptible trait: predisposition role of D1853N polymorphism in breast cancer.
|
20396981 |
2011 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Importance of ATM gene as a susceptible trait: predisposition role of D1853N polymorphism in breast cancer.
|
20396981 |
2011 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
We observed that the ATM 5557G>A polymorphism was significantly correlated with breast cancer risk when all studies were pooled into the meta-analysis (recessive model: odds ratio, OR = 0.67; 95% confidence interval (CI) 0.51-0.89).
|
20665102 |
2011 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
We observed that the ATM 5557G>A polymorphism was significantly correlated with breast cancer risk when all studies were pooled into the meta-analysis (recessive model: odds ratio, OR = 0.67; 95% confidence interval (CI) 0.51-0.89).
|
20665102 |
2011 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our results indicate that ATM D1853N polymorphism is not a risk factor for developing breast cancer.
|
20799949 |
2010 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our results indicate that ATM D1853N polymorphism is not a risk factor for developing breast cancer.
|
20799949 |
2010 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The results of this study might suggest a minor association between polymorphism 5557G>A and a reduced risk of breast cancer.
|
18264724 |
2008 |