Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
GRN-related frontotemporal dementia
CUI: C3811918
Disease: GRN-related frontotemporal dementia
0.030 GeneticVariation BEFREE Transmembrane Protein 106B SNP rs1990622 was recently shown to modify the risk of frontotemporal lobar degeneration with TDP-43 inclusions (FTD-TDP). 25096617 2015
GRN-related frontotemporal dementia
CUI: C3811918
Disease: GRN-related frontotemporal dementia
0.030 GeneticVariation BEFREE Recent large genome-wide association studies have found variants in TMEM106B (top SNP rs1990622) as a strong risk factor for frontotemporal lobar degeneration. 24166182 2014
GRN-related frontotemporal dementia
CUI: C3811918
Disease: GRN-related frontotemporal dementia
0.030 GeneticVariation BEFREE We investigated the rs1990622 polymorphism in relation to regional brain volumes to identify potential structures through which TMEM106B confers risk for frontotemporal lobar degeneration. 24731779 2014