Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE In addition to these factors, metabolic syndrome may also be related to genetic factors, the ADIPOQ + 45T> G polymorphism has been associated with serum adiponectin levels, insulin sensitivity, and obesity, which affects adiponectin levels act as protective factor for cardiovascular disease. 29313754 2019
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE The net effects of T45G polymorphism on the MAO phenotype may be achieved by changes in the adiponectin oligomer ratio and glucose levels. 27236826 2019
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE LEP rs7799039, LEPR rs1137101, and ADIPOQ rs2241766 and 1501299 Polymorphisms Are Associated With Obesity and Chemotherapy Response in Mexican Women With Breast Cancer. 28416193 2017
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE The results of this meta-analysis suggest that the ADIPOQ-rs2241766 G/T polymorphism might be associated with obesity in Chinese studies but not in non-Chinese studies in adults. 24740426 2014
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE Better-designed studies that consider confounding factors and assess larger sample sizes with a focus on ADIPOQ-rs2241766G/T polymorphisms and obesity are required in the future. 24740426 2014
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE However, there is no association between rs2241766 and obesity risk. 25223469 2014
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE We aimed to investigate the association of 45T>G single nucleotide polymorphism (SNP) in the adiponectin gene with total adiponectin levels, insulin resistance (IR), fasting blood glucose (FBG) and other markers of obesity in non-diabetic Saudi females. 23958652 2013
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE The rs2241766/rs3774261 haplotype was also associated with obesity (nominal p = 0.004). 19573164 2009
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE We explored potential associations of two single nucleotide polymorphisms (SNPs) in the adiponectin gene (ADIPOQ; +45T>G, rs2241766 and +276G>T, rs1501299) with circulating total and high-molecular weight (HMW) adiponectin, insulin resistance (IR), and markers of obesity in a healthy Greek female population. 19755407 2009
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE The aim of our study was to determine the frequency of single nucleotide polymorphisms (SNP) 45T>G and 276G>T of the adiponectin gene and 62G>A and -180C>G of the resistin gene in patients with obesity (OB), anorexia nervosa (AN) and in control healthy normal-weight women (NW) and to study the influence of particular genotypes on serum concentrations of these hormones and on insulin sensitivity. 17705672 2008
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE Previous findings that the ADIPOQ 45T-->G variant contributes to overall fatness and abdominal obesity are confirmed. 17209173 2007
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE Polymorphisms of 45T/G and 276G/T in APM1 gene are not associated with hypertension or obesity, or their clinical features in Chinese Han population. 16944773 2006
Obesity
CUI: C0028754
Disease: Obesity
0.100 GeneticVariation BEFREE The objective of this study was to examine the role of the adiponectin gene T45G polymorphism, located in exon 2, in PCOS, since this polymorphism has been shown to be associated with obesity and insulin resistance. 15178661 2004