rs2294008, PSCA;JRK

N. diseases: 28
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of urinary bladder
0.800 GeneticVariation GWASDB Our data identify rs2294008 as a new bladder cancer susceptibility locus. 19648920 2009
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.800 GeneticVariation BEFREE We found that rs2294008 and rs2976392, which were strongly linked to each other (D' = 1.00), were significantly associated with stomach cancer risk. 19582881 2009
Malignant neoplasm of urinary bladder
0.800 GeneticVariation BEFREE Our data identify rs2294008 as a new bladder cancer susceptibility locus. 19648920 2009
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.800 GeneticVariation GWASCAT Our data identify rs2294008 as a new bladder cancer susceptibility locus. 19648920 2009
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.800 GeneticVariation BEFREE Our data identify rs2294008 as a new bladder cancer susceptibility locus. 19648920 2009
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.100 GeneticVariation BEFREE Our data identify rs2294008 as a new bladder cancer susceptibility locus. 19648920 2009
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.100 GeneticVariation BEFREE We found that rs2294008 and rs2976392, which were strongly linked to each other (D' = 1.00), were significantly associated with stomach cancer risk. 19582881 2009
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.800 GeneticVariation BEFREE Recently, two genome-wide association studies identified a significant association between the prostate stem cell antigen (PSCA) rs2294008 (C>T) polymorphism and risk of diffuse-type of gastric cancer in Asians and bladder cancer in Caucasians, respectively. 20083643 2010
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.800 GeneticVariation GWASCAT A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. 20972438 2010
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.800 GeneticVariation BEFREE Two single nucleotide polymorphisms (SNPs) (rs2976392 and rs2294008) in the PSCA gene were recently identified as the susceptibility loci of gastric cancer, especially in diffuse type. 20131315 2010
Malignant neoplasm of urinary bladder
0.800 GeneticVariation GWASDB A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. 20972438 2010
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.800 GeneticVariation BEFREE These results indicated that the rs2294008 pol</span>ymorphism of PSCA gene may play a role in bladder cancer carcinogenesis and it could be served as a biomarker for genetic susceptibility to bladder cancer in Chinese populations. 20083643 2010
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.800 GeneticVariation BEFREE The rs2294008 C/T polymorphism of the PSCA gene was significantly associated with the susceptibility to GC. 20230293 2010
Malignant neoplasm of urinary bladder
0.800 GeneticVariation BEFREE These results indicated that the rs2294008 pol</span>ymorphism of PSCA gene may play a role in bladder cancer carcinogenesis and it could be served as a biomarker for genetic susceptibility to bladder cancer in Chinese populations. 20083643 2010
Nasopharyngeal carcinoma
CUI: C2931822
Disease: Nasopharyngeal carcinoma
0.700 GeneticVariation GWASDB A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. 20512145 2010
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.100 GeneticVariation BEFREE These results indicated that the rs2294008 pol</span>ymorphism of PSCA gene may play a role in bladder cancer carcinogenesis and it could be served as a biomarker for genetic susceptibility to bladder cancer in Chinese populations. 20083643 2010
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.100 GeneticVariation BEFREE The rs2294008 C/T polymorphism of the PSCA gene was significantly associated with the susceptibility to GC. 20230293 2010
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.100 GeneticVariation BEFREE Two single nucleotide polymorphisms (SNPs) (rs2976392 and rs2294008) in the PSCA gene were recently identified as the susceptibility loci of gastric cancer, especially in diffuse type. 20131315 2010
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.100 GeneticVariation BEFREE Recently, two genome-wide association studies identified a significant association between the prostate stem cell antigen (PSCA) rs2294008 (C>T) polymorphism and risk of diffuse-type of gastric cancer in Asians and bladder cancer in Caucasians, respectively. 20083643 2010
Carcinogenesis
CUI: C0596263
Disease: Carcinogenesis
0.040 GeneticVariation BEFREE These results indicated that the rs2294008 polymorphism of PSCA gene may play a role in bladder cancer carcinogenesis and it could be served as a biomarker for genetic susceptibility to bladder cancer in Chinese populations. 20083643 2010
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.800 GeneticVariation BEFREE The rs2294008 polymorphism in PSCA increases the risk of noncardia gastric cancer and its precursors in white individuals but protects against proximal cancers. 21070776 2011
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.800 GeneticVariation BEFREE Our study showed that rs2294008 in the PSCA gene was associated with increased risks of gastric cancer in a Korean population, suggests that rs2294008 might play an important role in gastric carcinogenesis. 21538581 2011
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.800 GeneticVariation BEFREE If validated in further studies, PSCA rs2294008</span> could be useful marker of sur</span>vival assessment and individualized clinical therapy for gastric cancer, particularly among the diffuse-type gastric cancer. 21064099 2011
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.800 GeneticVariation BEFREE In conclusion, The T allele of PSCA rs2294008 is associated with increased risk of gastric cancer, especially intestinal type, poorly differentiated, early onset, and noncardia gastric cancer in Chinese population. 21268123 2011
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.100 GeneticVariation BEFREE Our study showed that rs2294008 in the PSCA gene was associated with increased risks of gastric cancer in a Korean population, suggests that rs2294008 might play an important role in gastric carcinogenesis. 21538581 2011