|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
We also observed that the rs25487 mutation was significantly increased within the cervical cancer</span> population.
|
30616520 |
2019 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In view of the exiting heterogeneity, we did subgroup analysis stratified</span> by ethnicity, resulting in the fact that the Arg39</span>9Gln polymorphism was related to the decreased risk of cervical cancer.
|
27903984 |
2017 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis showed that the XRCC1 Arg399Gln GA variant might be risk alleles for cervical cancer susceptibility in the Chinese population, and further studies in other ethnic groups are required to arrive at definite conclusions.
|
27487002 |
2017 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In the subgroup analysis by ethnicity, the results also showed significant association between XRCC1 Ar</span>g399Gln polymorphism and susceptibility to cervical carcinoma in both Caucasian and Asian populations.
|
26345915 |
2015 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis provides strongly statistical evidence for the association between rs1799782 and cervical cancer risk, as well as its association with rs25487 only in Asian populations.
|
24057881 |
2014 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Gene polymorphism of XRCC1 Arg399Gln and cervical carcinoma susceptibility in Asians: a meta-analysis based on 1,759 cases and 2,497 controls.
|
23534722 |
2013 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The XRCC1 Arg399Gln genetic variants were identified by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in patients with advanced cervical cancer (n=189) and controls (n=308).
|
21928248 |
2012 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that Arg194Trp polymorphism may be associated with CC risk, Arg399Gln polymorphism might be a low-penetrent risk factor for CC only in Asians, and there may be no association between Arg280His polymorphism and CC risk.
|
22984511 |
2012 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
We found that the Arg194Trp polymorphism (Trp vs. Arg, OR=1.342, 95% CI: 1.176) was associated with increased risk of cervical cancer, while no significant association was found with Arg280His (His vs. Arg, OR=1.059, 95% CI: 0.863, 1.299) or Arg399Gln (Gln vs. Arg, OR=1.144, 95% CI: 0.938, 1.394).
|
23464469 |
2012 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
We found that compared with the Arg399Gln (GG), subjects carrying the homozygous Gln399Gln (AA) genotype had a significantly 2.32-fold increased risk of cerv</span>ical carcinoma (95% CI 1.47-3.65), heterozygous Arg399Gln (GA) genotype were also associated with a significantly increased risk of cervical carcinoma, with the adjusted odds ratio (OR) being 1.58 (95% CI 1.24-2.00).
|
17504380 |
2007 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
XRCC1 R399Q polymorphism is associated with response to platinum-based neoadjuvant chemotherapy in bulky cervical cancer.
|
16875718 |
2006 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of cervical cancer in Japanese subjects.
|
15990162 |
2005 |