rs25489, XRCC1

N. diseases: 78
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.050 GeneticVariation BEFREE Moreover, the AA genotype at rs25489 was determined to be a risk factor for cervical cancer etiology (homozygous model, OR 2.91, 95%CI, 1.17-7.26; recessive model, OR 3.16, 95%CI 1.91-5.24). 28415705 2017
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.050 GeneticVariation BEFREE Taken together, there was no obvious association between the Arg194Trp or Arg280His polymorphism and cervical cancer risk. 27903984 2017
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.050 GeneticVariation BEFREE However, there was no significant association between rs25489 and cervical cancer risk. 24057881 2014
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.050 GeneticVariation BEFREE We found that the Arg194Trp polymorphism (Trp vs. Arg, OR=1.342, 95% CI: 1.176) was associated with increased risk of cervical cancer, while no significant association was found with Arg280His (His vs. Arg, OR=1.059, 95% CI: 0.863, 1.299) or Arg399Gln (Gln vs. Arg, OR=1.144, 95% CI: 0.938, 1.394). 23464469 2012
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.050 GeneticVariation BEFREE This meta-analysis suggests that Arg194Trp polymorphism may be associated with CC risk, Arg399Gln polymorphism might be a low-penetrent risk factor for CC only in Asians, and there may be no association between Arg280His polymorphism and CC risk. 22984511 2012