rs25489, XRCC1

N. diseases: 78
Disease: Malignant neoplasm of prostate ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.030 GeneticVariation BEFREE And XRCC1-Arg280His polymorphism is likely to be related with prostate cancer risk under the heterozygote model and the dominant model. 25927275 2015
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.030 GeneticVariation BEFREE We conclude that the XRCC1 Arg280His polymorphism may be protective against the development of high-grade late toxicity after radiotherapy in prostate cancer patients. 21345510 2011
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.030 GeneticVariation BEFREE However, there was no significant risk of PCa associated with Arg280His polymorphism. 17486273 2007