Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Asthma
CUI: C0004096
Disease: Asthma
0.030 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) close to the gain-of-function substitution, Asn(107)Ile (rs324981, A>T), in Neuropeptide S Receptor 1 (NPSR1) have been associated with asthma. 28463995 2017
Asthma
CUI: C0004096
Disease: Asthma
0.030 GeneticVariation BEFREE Notably, this inhibition is absent in the asthma-linked N107I variant of NPSR, suggesting that residue 107 interacts with the aforementioned regulatory region of NPS. 16790440 2006
Asthma
CUI: C0004096
Disease: Asthma
0.030 GeneticVariation BEFREE Our study supports a role of the GPR154 gene in asthma susceptibility and suggests that the AA homozygote of rs324981 is a protective factor for airway hyperresponsiveness to methacholine in a Chinese population. 16522461 2006