rs3856806, PPARG

N. diseases: 41
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetes
CUI: C0011847
Disease: Diabetes
0.080 GeneticVariation BEFREE The TT genotype of rs3856806 in PPAR<i>γ</i> had an increased risk for diabetes. 29849618 2018
Diabetes
CUI: C0011847
Disease: Diabetes
0.080 GeneticVariation BEFREE The C1431T polymorphism of peroxisome proliferator activated receptor-γ (PPAR-γ) gene is related to diabetes and metabolic-syndrome. 25896411 2015
Diabetes
CUI: C0011847
Disease: Diabetes
0.080 GeneticVariation BEFREE The C1431T polymorphism in peroxisome proliferator-activated receptor-γ (PPARγ) has been shown to be associated with diabetes, obesity, and metabolic syndrome. 21643757 2012
Diabetes
CUI: C0011847
Disease: Diabetes
0.080 GeneticVariation BEFREE Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has been shown to be associated with body weight, but its association with diabetes is controversial. 21795447 2011
Diabetes
CUI: C0011847
Disease: Diabetes
0.080 GeneticVariation BEFREE Studies on the association of the Pro12Ala and C1431T polymorphisms of PPAR? with diabetes and obesity have revealed extensive population-dependent variations. 19805902 2009
Diabetes
CUI: C0011847
Disease: Diabetes
0.080 GeneticVariation BEFREE Based on published data from four populations, the date of origin of the diabetes protective PPARG Ala12 variant was estimated using both allele frequency and linkage disequilibrium (LD) with the C1431T single nucleotide polymorphism in exon 6 of the PPARG gene. 15994875 2005
Diabetes
CUI: C0011847
Disease: Diabetes
0.080 GeneticVariation BEFREE We have shown previously that the linked T allele of the C1431T polymorphism influences Ala12-associated diabetes risk and that the 2 polymorphisms have opposing associations with body weight. 15486307 2004
Diabetes
CUI: C0011847
Disease: Diabetes
0.080 GeneticVariation BEFREE The Pro12Ala polymorphism was more associated with plasma lipids and fasting glucose concentrations, whereas the C1431T polymorphism was related to the risk of diabetes. 14729856 2004