|
Diabetes
|
|
0.080 |
GeneticVariation
|
BEFREE |
The TT genotype of rs3856806 in PPAR<i>γ</i> had an increased risk for diabetes.
|
29849618 |
2018 |
|
Diabetes Mellitus
|
|
0.080 |
GeneticVariation
|
BEFREE |
The TT genotype of rs3856806 in PPAR<i>γ</i> had an increased risk for diabetes.
|
29849618 |
2018 |
|
Diabetes
|
|
0.080 |
GeneticVariation
|
BEFREE |
The C1431T polymorphism of peroxisome proliferator activated receptor-γ (PPAR-γ) gene is related to diabetes and metabolic-syndrome.
|
25896411 |
2015 |
|
Diabetes Mellitus
|
|
0.080 |
GeneticVariation
|
BEFREE |
The C1431T polymorphism of peroxisome proliferator activated receptor-γ (PPAR-γ) gene is related to diabetes and metabolic-syndrome.
|
25896411 |
2015 |
|
Diabetes Mellitus
|
|
0.080 |
GeneticVariation
|
BEFREE |
The C1431T polymorphism in peroxisome proliferator-activated receptor-γ (PPARγ) has been shown to be associated with diabetes, obesity, and metabolic syndrome.
|
21643757 |
2012 |
|
Diabetes
|
|
0.080 |
GeneticVariation
|
BEFREE |
The C1431T polymorphism in peroxisome proliferator-activated receptor-γ (PPARγ) has been shown to be associated with diabetes, obesity, and metabolic syndrome.
|
21643757 |
2012 |
|
Diabetes
|
|
0.080 |
GeneticVariation
|
BEFREE |
Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has been shown to be associated with body weight, but its association with diabetes is controversial.
|
21795447 |
2011 |
|
Diabetes Mellitus
|
|
0.080 |
GeneticVariation
|
BEFREE |
Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has been shown to be associated with body weight, but its association with diabetes is controversial.
|
21795447 |
2011 |
|
Diabetes Mellitus
|
|
0.080 |
GeneticVariation
|
BEFREE |
Studies on the association of the Pro12Ala and C1431T polymorphisms of PPAR? with diabetes and obesity have revealed extensive population-dependent variations.
|
19805902 |
2009 |
|
Diabetes
|
|
0.080 |
GeneticVariation
|
BEFREE |
Studies on the association of the Pro12Ala and C1431T polymorphisms of PPAR? with diabetes and obesity have revealed extensive population-dependent variations.
|
19805902 |
2009 |
|
Diabetes
|
|
0.080 |
GeneticVariation
|
BEFREE |
Based on published data from four populations, the date of origin of the diabetes protective PPARG Ala12 variant was estimated using both allele frequency and linkage disequilibrium (LD) with the C1431T single nucleotide polymorphism in exon 6 of the PPARG gene.
|
15994875 |
2005 |
|
Diabetes Mellitus
|
|
0.080 |
GeneticVariation
|
BEFREE |
Based on published data from four populations, the date of origin of the diabetes protective PPARG Ala12 variant was estimated using both allele frequency and linkage disequilibrium (LD) with the C1431T single nucleotide polymorphism in exon 6 of the PPARG gene.
|
15994875 |
2005 |
|
Diabetes Mellitus
|
|
0.080 |
GeneticVariation
|
BEFREE |
We have shown previously that the linked T allele of the C1431T polymorphism influences Ala12-associated diabetes risk and that the 2 polymorphisms have opposing associations with body weight.
|
15486307 |
2004 |
|
Diabetes
|
|
0.080 |
GeneticVariation
|
BEFREE |
We have shown previously that the linked T allele of the C1431T polymorphism influences Ala12-associated diabetes risk and that the 2 polymorphisms have opposing associations with body weight.
|
15486307 |
2004 |
|
Diabetes
|
|
0.080 |
GeneticVariation
|
BEFREE |
The Pro12Ala polymorphism was more associated with plasma lipids and fasting glucose concentrations, whereas the C1431T polymorphism was related to the risk of diabetes.
|
14729856 |
2004 |
|
Diabetes Mellitus
|
|
0.080 |
GeneticVariation
|
BEFREE |
The Pro12Ala polymorphism was more associated with plasma lipids and fasting glucose concentrations, whereas the C1431T polymorphism was related to the risk of diabetes.
|
14729856 |
2004 |
|
Obesity
|
|
0.070 |
GeneticVariation
|
BEFREE |
Our results support an important association between rs1805192 and rs3856806 minor allele (G allele) of PPARG and increased T2DM risk, the interaction analysis shown a combined effect of G- obesity interaction between rs1805192 and obesity on increased T2DM risk.
|
28123453 |
2017 |
|
Obesity
|
|
0.070 |
GeneticVariation
|
BEFREE |
The ProAla+AlaAla genotypes of PPAR-γ Pro12Ala were significantly associated with higher risk of obesity while C1431T polymorphism did not show any significant association.
|
22410809 |
2012 |
|
Obesity
|
|
0.070 |
GeneticVariation
|
BEFREE |
The C1431T polymorphism in peroxisome proliferator-activated receptor-γ (PPARγ) has been shown to be associated with diabetes, obesity, and metabolic syndrome.
|
21643757 |
2012 |
|
Obesity
|
|
0.070 |
GeneticVariation
|
BEFREE |
Mothers homozygous for the T allele of C1431T were also more obese (24 vs. 9%, P = 0.035), and three times more had gestational diabetes (18 vs. 6%, P = 0.044).
|
21795447 |
2011 |
|
Obesity
|
|
0.070 |
GeneticVariation
|
BEFREE |
Studies on the association of the Pro12Ala and C1431T polymorphisms of PPAR? with diabetes and obesity have revealed extensive population-dependent variations.
|
19805902 |
2009 |
|
Obesity
|
|
0.070 |
GeneticVariation
|
BEFREE |
The association of the C1431T silent mutation and the Pro12Ala missense transversion within the PPARgamma gene with the development of T2DM or obesity has often yielded contradictory results.
|
18250615 |
2007 |
|
Obesity
|
|
0.070 |
GeneticVariation
|
BEFREE |
The novel variants were, together with Pro12Ala and 1431C>T, examined for relationships with obesity among 234 men with early-onset obesity with a BMI at age approximately 20 years of 33.2+/-2.5 kg/m2 and 323 nonobese men with a BMI of 21.7+/-2.5 kg/m2, who were also reexamined after approximately 29 years.
|
15976135 |
2005 |
|
Metabolic Syndrome X
|
|
0.060 |
GeneticVariation
|
BEFREE |
Risk analysis of Kazakhs revealed that individuals with the CT and TT genotypes at rs3856806 had an increased risk, 0.524- and 0.770-fold, respectively, of developing MS than those possessing the CC genotype.
|
26125830 |
2015 |
|
Metabolic Syndrome X
|
|
0.060 |
GeneticVariation
|
BEFREE |
This study suggests that the PPARγ C1431T polymorphism is related to an increased risk of MetS in an Iranian population and interacts with the Pro12Ala polymorphism, further increasing the risk of MetS.
|
24464185 |
2014 |